Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 3/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.35 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3097743 | 0.97 | SLC1A2 (0.37) | SLC1A2SLC1A3SLC1A1OR51E2TDP1 | |
| SCHEMBL446242 | 0.81 | SLC1A2 (0.32) | SLC1A2SLC1A3SLC1A1OR51E2MCL1 | |
| Ammonia Solution, Strong SCHEMBL27845939 | 0.76 | — | — | |
| SCHEMBL9625411 | 0.74 | — | — | |
| SCHEMBL14381170 | 0.74 | MCL1 (0.33) | MCL1 | |
| SCHEMBL2437498 | 0.74 | — | — | |
| SCHEMBL10494506 | 0.74 | MEN1 (0.40) | TDP1MEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL6544793 | 0.74 | SLC1A1 (0.41) | SLC1A2SLC1A3SLC1A1OR51E2TDP1 | |
| SCHEMBL8413273 | 0.72 | — | — | |
| SCHEMBL2146574 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11035850-B2 | Quantitative determination of nucleoside analogue drugs in genomic DNA or RNA | THE JOHNS HOPKINS UNIVERSITY (US) | 2021-06-15 | — | — | US | disclosed |
| US-20200041488-A1 | QUANTITATIVE DETERMINATION OF NUCLEOSIDE ANALOGUE DRUGS IN GENOMIC DNA OR RNA | THE JOHNS HOPKINS UNIVERSITY | 2020-02-06 | — | — | US | disclosed |
| WO-2017180489-A1 | QUANTITATIVE DETERMINATION OF NUCLEOSIDE ANALOGUE DRUGS IN GENOMIC DNA OR RNA | THE JOHNS HOPKINS UNIVERSITY (US) | 2017-10-19 | — | — | WO | disclosed |
| US-20060293265-A1 | Methods involving aldose reductase inhibitors | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2006-12-28 | — | — | US | disclosed |
| US-20060210651-A1 | Methods and compositions involving aldose reductase | SRIVASTAVA SATISH K | 2006-09-21 | — | — | US | disclosed |
| WO-2003105864-A9 | METHODS AND COMPOSITIONS INVOLVING ALDOSE REDUCTASE INHIBITORS | UNIV TEXAS (US) | 2004-06-24 | — | — | WO | disclosed |
| US-20040047919-A1 | Methods and compositions involving aldose reductase inhibitors | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2004-03-11 | — | — | US | disclosed |
| WO-2003105864-A1 | METHODS AND COMPOSITIONS INVOLVING ALDOSE REDUCTASE INHIBITORS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2003-12-24 | — | — | WO | disclosed |