⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9523817 | 0.80 | — | — | |
| SCHEMBL1305300 | 0.78 | SLC1A2 (0.35) | — | |
| SCHEMBL28773374 | 0.77 | — | — | |
| SCHEMBL10011158 | 0.77 | GRIK1 (0.32) | — | |
| SCHEMBL15263375 | 0.76 | — | — | |
| SCHEMBL9487367 | 0.75 | SLC1A2 (0.48) | — | |
| SCHEMBL3097743 | 0.75 | SLC1A2 (0.37) | — | |
| SCHEMBL537504 | 0.74 | TDP1 (0.43) | — | |
| SCHEMBL29956584 | 0.74 | — | — | |
| Ammonia Solution, Strong SCHEMBL28482485 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110981806-A | Method for synthesizing aryl pyrazole nitrile and byproduct carbonic acid diester | 江苏优普生物化学科技股份有限公司 | 2020-04-10 | — | — | CN | claimed |
| CN-108349902-A | Process for preparing aminopyrazoles | 加尔达化学有限公司 | 2018-07-31 | — | — | CN | claimed |
| CN-108239031-A | The method for producing ethiprole intermediate by-product low-carbon ester | 曾舟华 | 2018-07-03 | — | — | CN | claimed |
| CN-108218781-A | The method of by-product low-carbon ester in ethiprole intermediate production process | 曾舟华 | 2018-06-29 | — | — | CN | claimed |
| CN-103502207-B | Process for preparing dicyanocarboxylate derivatives | Triumphant base Hall Mu Siji jar (unit of capacitance) reaches (IN) | 2016-01-27 | — | — | CN | claimed |
| CN-103214395-A | Synthesizing process of 2,3-dicyanoethylpropionate | NANTONG HAISHENG PHARMACEUTICAL CO LTD | 2013-07-24 | — | — | CN | claimed |
| CN-220531545-U | Ethyl 2, 3-dicyanopropionate recovery unit | 湖北金玉兰医药科技有限公司 | 2024-02-27 | — | — | CN | disclosed |
| CN-111689899-B | Stable isotope labeled fipronil and derivative thereof and synthetic preparation method | 上海出入境检验检疫局动植物与食品检验检疫技术中心 | 2023-06-02 | — | — | CN | disclosed |
| US-10993983-B2 | Cyclic peptide epitopes and small-molecule mimics for inducing autophagy | TRUSTEES OF TUFTS COLLEGE (US) | 2021-05-04 | — | — | US | disclosed |
| CN-111689899-A | Stable isotope labeled fipronil and its derivative and synthetic preparation method | 上海出入境检验检疫局动植物与食品检验检疫技术中心 | 2020-09-22 | — | — | CN | disclosed |
| CN-110981806-A | Method for synthesizing aryl pyrazole nitrile and byproduct carbonic acid diester | 江苏优普生物化学科技股份有限公司 | 2020-04-10 | — | — | CN | disclosed |
| CN-110981806-A | Method for synthesizing aryl pyrazole nitrile and byproduct carbonic acid diester | 江苏优普生物化学科技股份有限公司 | 2020-04-10 | — | — | CN | disclosed |
| CN-109575006-A | A kind of diazole pyrazole amide analog derivative and its microwave attenuation materials method and application | 中南民族大学 | 2019-04-05 | — | — | CN | disclosed |
| WO-2005023773-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED ARYL PYRAZOLES | PFIZER LIMITED (GB) | 2005-03-17 | — | — | WO | disclosed |
| EP-1264823-A1 | Process for the preparation of 2,3-dicyanopropionates | Novartis AG (CH) | 2002-12-11 | — | — | EP | disclosed |
| CN-1374306-A | Prepn of improved pesticide intermediate | JIANGSU PROV INST OF PESTICIDE (CN) | 2002-10-16 | — | — | CN | disclosed |
| EP-0888291-B1 | NEW PROCESS FOR PREPARING PESTICIDAL INTERMEDIATES | AVENTIS CROPSCIENCE SA (FR) | 2002-01-23 | — | — | EP | disclosed |
| US-6133432-A | REACTING A CYANOACETATE WITH A CYANIDE SALT AND FORMALDEHYDE OR A SOURCE OF FORMALDEHYDE | RHONE-POULENC AGRO (FR) | 2000-10-17 | — | — | US | disclosed |
| EP-0888291-A1 | NEW PROCESSES FOR PREPARING PESTICIDAL INTERMEDIATES | RHONE-POULENC AGROCHIMIE (FR) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997032843-A1 | NEW PROCESSES FOR PREPARING PESTICIDAL INTERMEDIATES | RHONE-POULENC AGROCHIMIE (FR) | 1997-09-12 | — | — | WO | disclosed |