Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.59 |
| ▸ | THRB | P10828 | 2/20 | 0.59 |
| ▸ | PTGER1 | P34995 | 6/20 | 0.54 |
| ▸ | PTGER4 | P35408 | 6/20 | 0.54 |
| ▸ | PTGER3 | P43115 | 6/20 | 0.54 |
| ▸ | PTGER2 | P43116 | 6/20 | 0.54 |
| ▸ | FFAR4 | Q5NUL3 | 9/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.53 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.49 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12394612 | 0.92 | THRA (0.49) | THRATHRBPTGER1PTGER4PTGER3 | |
| SCHEMBL2349977 | 0.88 | PTGER1 (0.47) | THRATHRBPTGER1PTGER4PTGER3 | |
| SCHEMBL2349128 | 0.88 | THRA (0.55) | THRATHRBFFAR4FFAR1 | |
| SCHEMBL2351164 | 0.86 | FFAR1 (0.70) | THRATHRBFFAR4FFAR1LTB4R | |
| SCHEMBL6063323 | 0.86 | FFAR4 (0.52) | THRATHRBFFAR4FFAR1 | |
| SCHEMBL6063119 | 0.84 | FFAR4 (0.67) | THRATHRBFFAR4FFAR1 | |
| SCHEMBL6064208 | 0.82 | THRA (0.75) | THRATHRBPTGER1PTGER4PTGER3 | |
| SCHEMBL6063960 | 0.82 | THRA (0.50) | THRATHRBPTGER1PTGER4PTGER3 | |
| SCHEMBL19181442 | 0.81 | THRA (0.71) | THRATHRBPTGER1PTGER4PTGER3 | |
| SCHEMBL2347446 | 0.81 | FFAR4 (0.67) | THRATHRBPTGER1PTGER4PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1688138-A1 | RECEPTOR FUNCTION REGULATING AGENT | Takeda Pharmaceutical Company Limited (JP) | 2006-08-09 | — | — | EP | disclosed |