Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | PTPRC | P08575 | 1/20 | 0.31 |
| ▸ | PTPRF | P10586 | 1/20 | 0.31 |
| ▸ | CDC25B | P30305 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6063227 | 0.78 | KMT2A (0.31) | SRD5A1PARP1ESR2MEN1KMT2A | |
| SCHEMBL30588973 | 0.66 | SMN1; SMN2 (0.42) | ESR2MEN1KMT2AACHEPOLB | |
| SCHEMBL23278853 | 0.65 | PARP3 (0.43) | HTR2AHTR2CHTR2BCYP19A1ALDH1A1 | |
| SCHEMBL30588920 | 0.65 | ESR2 (0.53) | PARP1ESR2CYP19A1PTPN1ALDH1A1 | |
| SCHEMBL11624145 | 0.65 | ESR2 (0.53) | PARP1ESR2CYP19A1PTPN1ALDH1A1 | |
| SCHEMBL21662201 | 0.64 | BRD4 (0.38) | HTR2AHTR2CHTR2BALDH1A1ACHE | |
| SCHEMBL2419305 | 0.63 | ESR2 (0.63) | HTR2AHTR2CHTR2BESR2CYP19A1 | |
| SCHEMBL15624258 | 0.63 | ACHE (0.42) | HTR2AHTR2CHTR2BMEN1KMT2A | |
| SCHEMBL822181 | 0.63 | ACHE (0.42) | HTR2AHTR2CHTR2BMEN1KMT2A | |
| SCHEMBL6062661 | 0.62 | ACHE (0.47) | HTR2AHTR2CHTR2BCYP19A1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7087599-B2 | Estrogen receptor modulators | MERCK & CO., INC. (US) | 2006-08-08 | — | — | US | disclosed |