Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.37 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6063377 | 1.00 | ALDH1A1 (0.44) | ALDH1A1PTPN2PTPN1POLBMAPT | |
| SCHEMBL6687626 | 0.85 | PTPN2 (0.37) | PTPN2PTPN1 | |
| SCHEMBL5424669 | 0.85 | PTPN1 (0.41) | ALDH1A1PTPN2PTPN1MAPTHPGD | |
| SCHEMBL5424670 | 0.85 | PTPN1 (0.41) | ALDH1A1PTPN2PTPN1MAPTHPGD | |
| SCHEMBL6063374 | 0.84 | ALDH1A1 (0.41) | ALDH1A1PTPN2PTPN1MAPTHPGD | |
| SCHEMBL6632738 | 0.84 | PTPN1 (0.38) | ALDH1A1PTPN2PTPN1MAPTHPGD | |
| SCHEMBL6630202 | 0.84 | PTPN1 (0.38) | ALDH1A1PTPN2PTPN1MAPTHPGD | |
| SCHEMBL6702111 | 0.84 | PTPN1 (0.38) | ALDH1A1PTPN2PTPN1MAPTHPGD | |
| SCHEMBL6702107 | 0.84 | PTPN1 (0.38) | ALDH1A1PTPN2PTPN1MAPTHPGD | |
| SCHEMBL6695960 | 0.84 | PTPN1 (0.38) | ALDH1A1PTPN2PTPN1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1694357-A1 | USE OF CATHEPSIN S INHIBITORS FOR TREATING AN IMMUNE RESPONSE CAUSED BY ADMINISTRATION OF A SMALL MOLECULE THERAPEUTIC OR BIOLOGIC | AXYS PHARMACEUTICALS, INC. (US) | 2006-08-30 | — | — | EP | disclosed |
| WO-2005058348-A1 | USE OF CATHEPSIN S INHIBITORS FOR TREATING AN IMMUNE RESPONSE CAUSED BY ADMINISTRATION OF A SMALL MOLECULE THERAPEUTIC OR BIOLOGIC | AXYS PHARMACEUTICALS, INC. (US) | 2005-06-30 | — | — | WO | disclosed |