Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 9/20 | 0.57 |
| ▸ | NOS1 | P29475 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PAH | P00439 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL336072 | 0.91 | HPRT1 (0.55) | HPRT1NOS1USP2CASP7HSD17B10 | |
| Water SCHEMBL10601101 | 0.90 | HPRT1 (0.54) | HPRT1NOS1USP2CASP7HSD17B10 | |
| Ammonia Solution, Strong SCHEMBL10901621 | 0.90 | HPRT1 (0.54) | HPRT1NOS1USP2CASP7HSD17B10 | |
| Phosphoric Acid SCHEMBL9471917 | 0.87 | HPRT1 (0.59) | HPRT1NOS1USP2CASP7HSD17B10 | |
| SCHEMBL2775722 | 0.84 | HPRT1 (0.55) | HPRT1NOS1USP2CASP7HSD17B10 | |
| SCHEMBL147641 | 0.82 | HPRT1 (0.67) | HPRT1NOS1USP2CASP7HSD17B10 | |
| SCHEMBL7132437 | 0.81 | HPRT1 (0.60) | HPRT1NOS1USP2CASP7HSD17B10 | |
| SCHEMBL10643032 | 0.80 | HPRT1 (0.56) | HPRT1NOS1USP2CASP7HSD17B10 | |
| SCHEMBL8149575 | 0.78 | HPRT1 (0.60) | HPRT1NOS1USP2HSD17B10ALDH1A1 | |
| SCHEMBL1635327 | 0.77 | HPRT1 (0.55) | HPRT1NOS1USP2CASP7HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2967078-B1 | THYMIDINE KINASE DIAGNOSTIC ASSAY FOR GENE THERAPY APPLICATIONS | GENVIVO INC (US) | 2018-10-17 | — | — | EP | claimed |
| WO-2013048952-A1 | METHODS AND COMPOSITIONS FOR DETECTING INFECTIONS | BIOMED VALLEY DISCOVERIES, INC. (US) | 2013-04-04 | — | — | WO | claimed |
| CN-110129344-B | Improved thymidine kinase gene | 吉恩维沃公司 | 2024-06-18 | — | — | CN | disclosed |
| US-10610603-B2 | Thymidine kinase gene | Genvivo, Inc. (US) | 2020-04-07 | — | — | US | disclosed |
| US-20190328904-A1 | THYMIDINE KINASE DIAGNOSTIC ASSAY FOR GENE THERAPY APPLICATIONS | Genvivo, Inc. | 2019-10-31 | — | — | US | disclosed |
| US-10350302-B2 | Thymidine kinase diagnostic assay for gene therapy applications | Genvivo, Inc. (US) | 2019-07-16 | — | — | US | disclosed |
| US-20180264137-A1 | THYMIDINE KINASE DIAGNOSTIC ASSAY FOR GENE THERAPY APPLICATIONS | Genvivo, Inc. | 2018-09-20 | — | — | US | disclosed |
| US-20180236101-A1 | THYMIDINE KINASE GENE | Genvivo, Inc. | 2018-08-23 | — | — | US | disclosed |
| WO-2013128022-A1 | METHOD FOR PREVENTING OR TREATING A HEPATITIS C VIRUS INFECTION OR A HEPATITIS B VIRUS INFECTION BY ADMINISTRATION OF SUICIDE GENE-MODIFIED LYMPHOCYTES | UNIVERSITÉ DE STRASBOURG (FR) | 2013-09-06 | — | — | WO | disclosed |
| WO-2013048952-A1 | METHODS AND COMPOSITIONS FOR DETECTING INFECTIONS | BIOMED VALLEY DISCOVERIES, INC. (US) | 2013-04-04 | — | — | WO | disclosed |
| US-8357832-B2 | F1B-TMIR plasmid vector and transgenic mouse | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2013-01-22 | — | — | US | disclosed |
| US-20120144507-A1 | F1B-TMIR PLASMID VECTOR AND TRANSGENIC MOUSE | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2012-06-07 | — | — | US | disclosed |
| US-8129181-B2 | F1B-TMIR plasmid vector and transgenic mouse | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2012-03-06 | — | — | US | disclosed |
| US-20110023136-A1 | F1B-TMIR Plasmid Vector and Transgenic Mouse | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2011-01-27 | — | — | US | disclosed |
| US-6331287-B1 | NONCATABOLIZING IMAGING AGENT FOR POSITRON EMISSION TOMOGRAPHY; | UNIVERSITY ADVANCED BIO-IMAGING ASSOCIATES | 2001-12-18 | — | — | US | disclosed |
| WO-1999044646-A1 | NOVEL IMAGING AGENTS AND METHODS FOR THE PREPARATION AND USE THEREOF | UNIVERSITY ADVANCED BIO-IMAGING ASSOCIATES (US) | 1999-09-10 | — | — | WO | disclosed |
| US-5879661-A | Imaging agents and methods for the preparation and use thereof | UNIVERSITY ADVANCED BIO-IMAGING ASSOCIATES (US) | 1999-03-09 | — | — | US | disclosed |