Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 9/20 | 0.68 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | GAK | O14976 | 1/20 | 0.41 |
| ▸ | STK17B | O94768 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | NEK2 | P51955 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5523882 | 0.85 | NOS1 (0.74) | NOS1PIK3CGGAKSTK17BPIK3CA | |
| SCHEMBL5513759 | 0.83 | NOS1 (0.84) | NOS1PIK3CGGAK | |
| Water SCHEMBL6483778 | 0.82 | NOS1 (0.82) | NOS1PIK3CGGAK | |
| SCHEMBL5513505 | 0.81 | NOS1 (1.00) | NOS1PIK3CGGAK | |
| SCHEMBL6063542 | 0.81 | NOS1 (0.67) | NOS1PIK3CGSYKGAKSTK17B | |
| Water SCHEMBL6483075 | 0.80 | NOS1 (0.98) | NOS1PIK3CGGAK | |
| SCHEMBL4454683 | 0.79 | NOS1 (0.60) | NOS1PIK3CGSYKGAKSTK17B | |
| SCHEMBL4449231 | 0.79 | NOS1 (0.60) | NOS1PIK3CGSYKGAKSTK17B | |
| SCHEMBL5508808 | 0.78 | NOS1 (1.00) | NOS1PIK3CGMAPK1 | |
| SCHEMBL5514530 | 0.78 | NOS1 (0.59) | NOS1PIK3CGSYKGAKSTK17B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658081-A2 | IMMUNOSUPPRESSIVE EFFECTS OF PTERIDINE DERIVATIVES | 4 AZA Bioscience nv (BE) | 2006-05-24 | — | — | EP | claimed |
| WO-2005021003-A2 | IMMUNOSUPPRESSIVE EFFECTS OF PTERIDINE DERIVATIVES | 4 AZA BIOSCIENCE NV (BE) | 2005-03-10 | — | — | WO | claimed |