SCHEMBL6064256

SCHEMBL6064256

CO[Si](C)(CCC1CC2C=CC1C2)OC

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.39
ALDH1A1 P00352 3/20 0.39
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
HTT P42858 1/20 0.33
TSHR P16473 1/20 0.32
POLB P06746 1/20 0.32
ALOX15 P16050 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6063758 0.90 KDM4E (0.37) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL6063818 0.89 KDM4E (0.36) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL6062705 0.87 ALDH1A1 (0.36) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL6064093 0.87 ALDH1A1 (0.36) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL6063400 0.87 ALDH1A1 (0.36) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL1760598 0.86 KDM4E (0.39) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL4661357 0.85 KDM4E (0.38) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL15802770 0.85 KDM4E (0.38) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL115037 0.84 KDM4E (0.40) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL16335885 0.84 KDM4E (0.40) KDM4EALDH1A1MEN1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0539901-B1 Process for producing thermoplastic resin JAPAN SYNTHETIC RUBBER CO LTD (JP) 1996-02-28 EP claimed
EP-0539901-A1 Process for producing thermoplastic resin JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1993-05-05 EP claimed
US-20230250248-A1 CATALYST-FREE SURFACE FUNCTIONALIZATION AND POLYMER GRAFTING ILLUMINA, INC. 2023-08-10 US disclosed
US-9994687-B2 Catalyst-free surface functionalization and polymer grafting ILLUMINA, INC. (US) 2018-06-12 US disclosed
US-20160289372-A1 POLYMERIZABLE COMPOSITION, RESIN SHAPED ARTICLE, COMPOSITE, AND LAMINATE ZEON CORPORATION (JP) 2016-10-06 US disclosed
WO-2015133513-A1 MULTILAYER CURABLE RESIN FILM, PRE-PREG, LAMINATE BODY, CURED PRODUCT, COMPLEX, AND MULTILAYER CIRCUIT BOARD 日本ゼオン株式会社 2015-09-11 WO disclosed
US-20150005447-A1 CATALYST-FREE SURFACE FUNCTIONALIZATION AND POLYMER GRAFTING ILLUMINA, INC. 2015-01-01 US disclosed
US-7015292-B2 Silicon-containing olefin copolymer, crosslinkable rubber composition thereof, and use thereof MITSUI CHEMICALS, INC. (JP) 2006-03-21 US disclosed
US-20050038214-A1 Silicon-containing olefin copolymer, crosslinkable rubber composition thereof, and use thereof MITSUI CHEMICALS, INC. (JP) 2005-02-17 US disclosed
EP-0539901-B1 Process for producing thermoplastic resin JAPAN SYNTHETIC RUBBER CO LTD (JP) 1996-02-28 EP disclosed
US-5274053-A Grafting a vinyl monomer to a modified polyorganosiloxane and crosslinking with an alkoxysilane having an azo or disulfide group JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1993-12-28 US disclosed
EP-0539901-A1 Process for producing thermoplastic resin JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1993-05-05 EP disclosed