SCHEMBL6064271

SCHEMBL6064271

CCOC(C[SiH2]CCC1CC2C=CC1C2)OCC

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.41
ALDH1A1 P00352 2/20 0.41
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
HTT P42858 1/20 0.32
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6064362 0.87 KDM4E (0.39) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL6063124 0.85 KDM4E (0.40) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL6064285 0.81 KDM4E (0.42) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL6062956 0.80 KDM4E (0.42) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL15150834 0.78 KDM4E (0.47) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL6064468 0.75 KDM4E (0.45) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL15805497 0.72 KDM4E (0.47) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL6064045 0.71 KDM4E (0.44) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL6064037 0.71 KDM4E (0.41) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL6063197 0.71 KDM4E (0.37) KDM4EALDH1A1MEN1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7015292-B2 Silicon-containing olefin copolymer, crosslinkable rubber composition thereof, and use thereof MITSUI CHEMICALS, INC. (JP) 2006-03-21 US disclosed
US-20050038214-A1 Silicon-containing olefin copolymer, crosslinkable rubber composition thereof, and use thereof MITSUI CHEMICALS, INC. (JP) 2005-02-17 US disclosed