Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 8/20 | 0.52 |
| ▸ | SCN3A | Q9NY46 | 11/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.47 |
| ▸ | SCN1A | P35498 | 1/20 | 0.47 |
| ▸ | SCN4A | P35499 | 1/20 | 0.47 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.47 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.47 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.43 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5481350 | 1.00 | KCNH2 (0.52) | KCNH2SCN3ASCN9ASCN1ASCN4A | |
| SCHEMBL5481360 | 1.00 | KCNH2 (0.52) | KCNH2SCN3ASCN9ASCN1ASCN4A | |
| SCHEMBL5481355 | 1.00 | KCNH2 (0.52) | KCNH2SCN3ASCN9ASCN1ASCN4A | |
| SCHEMBL5490109 | 0.91 | KDM1A (0.47) | KCNH2SCN3ASCN9ASCN1ASCN4A | |
| SCHEMBL5483694 | 0.89 | SCN3A (0.58) | KCNH2SCN3ASCN9ASCN1ASCN4A | |
| SCHEMBL5493109 | 0.88 | KDM1A (0.57) | KCNH2KDM1ASPHK2SPHK1 | |
| SCHEMBL5488311 | 0.86 | SCN3A (0.46) | KCNH2SCN3ASCN9ASCN1ASCN4A | |
| SCHEMBL5484369 | 0.84 | KMT2A (0.47) | KCNH2SCN3ASCN9ASCN1ASCN4A | |
| SCHEMBL5484837 | 0.84 | SCN3A (0.44) | KCNH2SCN3ASCN9ASCN1ASCN4A | |
| SCHEMBL5484364 | 0.84 | KCNH2 (0.45) | KCNH2SCN3ASCN9ASCN1ASCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1687259-A1 | CYCLOPENTYL DERIVATES | Newron Pharmaceuticals S.p.A. (IT) | 2006-08-09 | — | — | EP | claimed |
| WO-2005054178-A1 | CYCLOPENTYL DERIVATIVES | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2005-06-16 | — | — | WO | claimed |