Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 7/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.46 |
| ▸ | HPD | P32754 | 1/20 | 0.45 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.42 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.41 |
| ▸ | SCN4A | P35499 | 1/20 | 0.41 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5481355 | 0.91 | KCNH2 (0.52) | KDM1ASCN3AKCNH2HPDSPHK2 | |
| SCHEMBL6064341 | 0.91 | KCNH2 (0.52) | KDM1ASCN3AKCNH2HPDSPHK2 | |
| SCHEMBL5481350 | 0.91 | KCNH2 (0.52) | KDM1ASCN3AKCNH2HPDSPHK2 | |
| SCHEMBL5481360 | 0.91 | KCNH2 (0.52) | KDM1ASCN3AKCNH2HPDSPHK2 | |
| Carbamic Acid SCHEMBL5491782 | 0.82 | SCN3A (0.52) | SCN3AKCNH2HPDSPHK2SPHK1 | |
| SCHEMBL5493109 | 0.80 | KDM1A (0.57) | KDM1AKCNH2SPHK2SPHK1 | |
| SCHEMBL5483694 | 0.80 | SCN3A (0.58) | SCN3AKCNH2MAOBLPAR1LPAR5 | |
| SCHEMBL5488311 | 0.77 | SCN3A (0.46) | SCN3AKCNH2MAOBSCN1ASCN4A | |
| SCHEMBL5394785 | 0.76 | HPGD (0.51) | KDM1ASSTR3F2SCN9A | |
| SCHEMBL372599 | 0.76 | HPGD (0.51) | KDM1ASSTR3F2SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1687259-B1 | CYCLOPENTYL DERIVATES | NEWRON PHARM SPA (IT) | 2007-08-08 | — | — | EP | disclosed |