Ditiocarb

Ditiocarb

SCHEMBL6064688

CC(C)N(C)C(C)C.CCN(CC)C(=S)S

nearest known ligand 0.68

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCB11 O95342 2/20 0.68
HTT P42858 2/20 0.68
GSDMD P57764 2/20 0.68
CYP2E1 P05181 1/20 0.68
PTGS1 P23219 1/20 0.68
EHMT2 Q96KQ7 3/20 0.37
EHMT1 Q9H9B1 3/20 0.37
CA12 O43570 2/20 0.37
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
CA4 P22748 2/20 0.37
CA9 Q16790 2/20 0.37
PHGDH O43175 3/20 0.36
MGLL Q99685 3/20 0.36
ALDH1A1 P00352 3/20 0.36
CYP2C9 P11712 2/20 0.36
HPGD P15428 2/20 0.36
HSD17B10 Q99714 2/20 0.36
ALDH2 P05091 2/20 0.36
PLIN1 O60240 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ditiocarb SCHEMBL8986653 0.83 ABCB11 (0.88) ABCB11HTTGSDMDCYP2E1PTGS1
Ditiocarb SCHEMBL30777192 0.83 ABCB11 (1.00) ABCB11HTTGSDMDCYP2E1PTGS1
Ditiocarb SCHEMBL48382 0.83
Ditiocarb SCHEMBL3140725 0.82 ABCB11 (0.68) ABCB11HTTGSDMDCYP2E1PTGS1
Ditiocarb SCHEMBL25284941 0.80 ABCB11 (0.94) ABCB11HTTGSDMDCYP2E1PTGS1
Ditiocarb SCHEMBL2236180 0.80
Ditiocarb SCHEMBL7898491 0.80
Ditiocarb SCHEMBL21801890 0.80
Ditiocarb SCHEMBL21359739 0.80 ABCB11 (0.94) ABCB11HTTGSDMDCYP2E1PTGS1
Ditiocarb SCHEMBL16735397 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060057566-A1 METHODS AND COMPOSITIONS FOR ANALYZING NUCLEIC ACID MOLECULES UTILIZING SIZING TECHNIQUES QIAGEN GENOMICS, INC. (US) 2006-03-16 US disclosed