Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | GGH | Q92820 | 1/20 | 0.48 |
| ▸ | PYGL | P06737 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.46 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CCKAR | P32238 | 3/20 | 0.45 |
| ▸ | CCKBR | P32239 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27565835 | 1.00 | NAALAD2 (0.51) | NAALAD2GAAGGHPYGLCA2 | |
| SCHEMBL300104 | 0.84 | KDM4E (0.46) | CA2CA1HSD17B10CCKARCCKBR | |
| SCHEMBL29732414 | 0.83 | PYGL (0.54) | NAALAD2GAAGGHPYGLCA2 | |
| SCHEMBL14606037 | 0.83 | PYGL (0.54) | NAALAD2GAAGGHPYGLCA2 | |
| SCHEMBL9615846 | 0.83 | PYGL (0.54) | NAALAD2GAAGGHPYGLCA2 | |
| SCHEMBL3459202 | 0.83 | PYGL (0.50) | PYGLFOLH1CCKARCCKBR | |
| SCHEMBL30615312 | 0.82 | NAALAD2 (0.56) | NAALAD2GAAGGHCA2CA1 | |
| SCHEMBL29772335 | 0.82 | NAALAD2 (0.56) | NAALAD2GAAGGHCA2CA1 | |
| SCHEMBL4775100 | 0.82 | NAALAD2 (0.56) | NAALAD2GAAGGHCA2CA1 | |
| SCHEMBL30615313 | 0.82 | NAALAD2 (0.56) | NAALAD2GAAGGHCA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102399224-B | Preparation method of low-iron methotrexate | HUZHOU ZHANWANG PHARMACEUTICAL CO LTD | 2013-10-02 | — | — | CN | claimed |
| CN-102399224-B | Preparation method of low-iron methotrexate | HUZHOU ZHANWANG PHARMACEUTICAL CO LTD | 2013-10-02 | — | — | CN | disclosed |
| CN-102399224-A | Preparation method of low-iron methotrexate | HUZHOU ZHANWANG PHARMACEUTICAL CO LTD | 2012-04-04 | — | — | CN | disclosed |
| CN-1283641-C | Pteridine derivatives with nitric oxide synthase inhibitor function | UNIV CHINA PHARMA (CN) | 2006-11-08 | — | — | CN | disclosed |
| WO-2006074416-A1 | 5-AMINO-4-IMIDAZOLECARBOXAMIDE RIBOSIDE AND ITS NUCLEOBASE AS POTENTIATORS OF ANTIFOLATE TRANSPORT AND METABOLISM | HEALTH RESEARCH INC. (US) | 2006-07-13 | — | — | WO | disclosed |
| CN-1546491-A | Pteridine derivatives with nitric oxide synthase inhibitor function | 中国药科大学 | 2004-11-17 | — | — | CN | disclosed |