SCHEMBL6065273

SCHEMBL6065273

Fc1cc(-c2ccccc2F)ccc1I

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 1/20 0.52
PTPN1 P18031 1/20 0.52
ACMSD Q8TDX5 1/20 0.46
FEN1 P39748 4/20 0.45
ALOX5AP P20292 3/20 0.45
TNKS O95271 1/20 0.45
TNKS2 Q9H2K2 1/20 0.45
BACE1 P56817 1/20 0.45
TRPA1 O75762 1/20 0.45
PDK2 Q15119 1/20 0.44
MAP4K4 O95819 1/20 0.42
CYP11B1 P15538 1/20 0.41
CYP11B2 P19099 1/20 0.41
NPSR1 Q6W5P4 1/20 0.40
PIK3R1 P27986 1/20 0.40
PIK3CA P42336 1/20 0.40
ALDH1A1 P00352 1/20 0.40
MAPT P10636 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
PGR P06401 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18759011 0.83 PTPRC (0.52) PTPRCPTPN1ACMSDFEN1ALOX5AP
SCHEMBL503183 0.82 FEN1 (0.44) PTPRCPTPN1FEN1ALOX5APCYP11B1
SCHEMBL13439490 0.80 PTPRC (0.57) PTPRCPTPN1ACMSDFEN1ALOX5AP
SCHEMBL30665733 0.80 PTPRC (0.57) PTPRCPTPN1ACMSDFEN1ALOX5AP
SCHEMBL23349943 0.78 HSD17B1 (0.42) CYP11B1CYP11B2ALDH1A1MAPT
SCHEMBL24017170 0.78 TTR (0.47) ACMSDFEN1ALOX5APALDH1A1DHODH
SCHEMBL17951222 0.77 PTPRC (0.58) PTPRCPTPN1ACMSDFEN1ALOX5AP
SCHEMBL16850562 0.77 PTPRC (0.58) PTPRCPTPN1ACMSDFEN1ALOX5AP
SCHEMBL12856701 0.77 PTPRC (0.56) PTPRCPTPN1ACMSDFEN1ALOX5AP
SCHEMBL27907800 0.76 MAPT (0.47) PTPRCPTPN1ACMSDBACE1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7125589-B1 Liquid crystal compound having hydrogen as a terminal group, composition comprising the compound, and liquid crystal display element comprising the composition CHISSO CORPORATION (JP) 2006-10-24 US disclosed
EP-1352886-A1 Liquid crystal compound having hydrogen as a terminal group, composition comprising the compound, and liquid crystal display element comprising the composition CHISSO CORPORATION (JP) 2003-10-15 EP disclosed