Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 3/20 | 0.33 |
| ▸ | JAK2 | O60674 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5403833 | 0.78 | CHRM2 (0.37) | MAPK1CHRM2CHRM1CHRM3BTK | |
| SCHEMBL186721 | 0.77 | HRH3 (0.51) | HRH3MAPK1CHRM2CHRM1CHRM3 | |
| SCHEMBL1295721 | 0.77 | HRH3 (0.51) | HRH3MAPK1CHRM2CHRM1CHRM3 | |
| SCHEMBL28492122 | 0.77 | HRH3 (0.51) | HRH3MAPK1CHRM2CHRM1CHRM3 | |
| SCHEMBL1296976 | 0.76 | HRH3 (0.41) | HRH3MAPK1JAK1JAK2CHRM2 | |
| SCHEMBL1409867 | 0.76 | HRH3 (0.41) | HRH3MAPK1JAK1JAK2CHRM2 | |
| SCHEMBL7641822 | 0.75 | ALDH1A1 (0.36) | HRH3MAPK1CHRM2CHRM1CHRM3 | |
| SCHEMBL22263842 | 0.74 | KDM4E (0.37) | HRH3HPGD | |
| SCHEMBL1586789 | 0.74 | HRH3 (0.41) | HRH3MAPK1JAK1JAK2CHRM2 | |
| SCHEMBL4228795 | 0.74 | SMN1; SMN2 (0.42) | HRH3CHRM2CHRM1CHRM3BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1626999-A1 | OLEFIN POLYMERIZATION CATALYST SYSTEM USEFUL FOR POLAR MONOMERS | Exxonmobil Chemical Patents Inc. (US) | 2006-02-22 | — | — | EP | disclosed |
| WO-2004101634-A1 | OLEFIN POLYMERIZATION CATALYST SYSTEM USEFUL FOR POLAR MONOMERS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-11-25 | — | — | WO | disclosed |