SCHEMBL6065367

SCHEMBL6065367

O=C(CC(O)c1ccccc1)NC1N=C(c2ccccc2)c2ccccc2NC1=O.O=C(NC1N=C(c2ccccc2)c2ccccc2NC1=O)C(O)Cc1ccccc1

nearest known ligand 0.66

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CCKBR P32239 18/20 0.58
CCKAR P32238 13/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL643214 0.91 CCKBR (0.63) CCKBRCCKAR
SCHEMBL642034 0.91 CCKBR (0.67) CCKBRCCKAR
SCHEMBL9866463 0.80 CCKBR (0.66) CCKBRCCKAR
SCHEMBL9866460 0.80 CCKBR (0.66) CCKBRCCKAR
SCHEMBL9866450 0.80 CCKBR (0.66) CCKBRCCKAR
SCHEMBL16110814 0.80 CCKBR (0.64) CCKBRCCKAR
SCHEMBL643257 0.78 CCKBR (0.64) CCKBRCCKAR
SCHEMBL643277 0.76 CCKBR (0.68) CCKBRCCKAR
SCHEMBL644129 0.75 CCKBR (0.69) CCKBRCCKAR
SCHEMBL2930364 0.75 CCKBR (0.76) CCKBRCCKAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8853204-B2 Pharmaceutical composition comprising a benzodiazepine derivative and an inhibitor of the RSV fusion protein ARROW THERAPEUTICS LIMITED (GB) 2014-10-07 US claimed
EP-1727550-A1 PHARMACEUTICAL COMPOSITION COMPRISING A BENZODIAZEPINE DERIVATIVE AND AN INHIBITOR OF THE RSV FUSION PROTEIN Arrow Therapeutics Limited (GB) 2006-12-06 EP claimed
WO-2005089769-A1 PHARMACEUTICAL COMPOSITION COMPRISING A BENZODIAZEPINE DERIVATIVE AND AN INHIBIT OR OF THE RSV FUSION PROTEIN ARROW THERAPEUTICS LIMITED (GB) 2005-09-29 WO claimed
EP-1727550-A1 PHARMACEUTICAL COMPOSITION COMPRISING A BENZODIAZEPINE DERIVATIVE AND AN INHIBITOR OF THE RSV FUSION PROTEIN Arrow Therapeutics Limited (GB) 2006-12-06 EP disclosed
WO-2005090319-A1 PROCESS FOR PREPARING BENZODIAZEPINES ARROW THERAPEUTICS LIMITED (GB) 2005-09-29 WO disclosed
WO-2005089769-A1 PHARMACEUTICAL COMPOSITION COMPRISING A BENZODIAZEPINE DERIVATIVE AND AN INHIBIT OR OF THE RSV FUSION PROTEIN ARROW THERAPEUTICS LIMITED (GB) 2005-09-29 WO disclosed