Doxecitine

Doxecitine

SCHEMBL6066348

Nc1ccn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)n1.O=P(O)(O)OP(=O)(O)OP(=O)(O)O

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.69
▸ P2RY2 P41231 4/20 0.59
▸ P2RY4 P51582 3/20 0.59
▸ P2RY6 Q15077 2/20 0.59
▸ POLG P54098 2/20 0.59
▸ DNMT1 P26358 2/20 0.55
▸ ADRB1 P08588 1/20 0.55
▸ LMNA P02545 4/20 0.52
▸ THRB P10828 1/20 0.52
▸ MTOR P42345 1/20 0.52
▸ MDM2 Q00987 1/20 0.52
▸ NCOA1 Q15788 1/20 0.52
▸ NCOA3 Q9Y6Q9 1/20 0.52
▸ PDE3A Q14432 4/20 0.50
▸ CACNA1F O60840 2/20 0.50
▸ ALB P02768 2/20 0.50
▸ MAPT P10636 2/20 0.50
▸ CACNA1D Q01668 2/20 0.50
▸ CACNA1S Q13698 2/20 0.50
▸ CACNA1C Q13936 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Doxecitine SCHEMBL2506914 0.96 POLB (0.72) POLBP2RY2P2RY4P2RY6POLG
Doxecitine SCHEMBL2027315 0.92 POLB (0.67) POLBP2RY2P2RY4P2RY6POLG
Doxecitine SCHEMBL1971065 0.92 POLB (0.67) POLBP2RY2P2RY4P2RY6POLG
Doxecitine SCHEMBL21643137 0.92 POLB (0.67) POLBP2RY2P2RY4P2RY6POLG
Doxecitine SCHEMBL4862620 0.90 POLB (0.64) POLBP2RY2P2RY4P2RY6POLG
Doxecitine SCHEMBL18149017 0.90 POLB (0.64) POLBP2RY2P2RY4P2RY6POLG
Doxecitine SCHEMBL23346798 0.90 DNMT1 (0.66) POLBP2RY2P2RY4P2RY6DNMT1
Doxecitine SCHEMBL887491 0.90 DNMT1 (0.66) POLBP2RY2P2RY4P2RY6DNMT1
Doxecitine SCHEMBL15832461 0.90 DNMT1 (0.66) POLBP2RY2P2RY4P2RY6DNMT1
Doxecitine SCHEMBL10238960 0.90 DNMT1 (0.66) POLBP2RY2P2RY4P2RY6DNMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105849251-A Nucleoside supplementation for promoting cellular function, genetic stability and regenerative applications 加利福尼亚大学董事会 2016-08-10 — — CN claimed
CN-110499361-A A kind of preparation method and application of terminal bases streaming fluorescence sequencing microballoon UNIV QILU TECHNOLOGY 2019-11-26 — — CN disclosed
CN-103492865-B It determines the method for the base sequence of polynucleotides and determines the device of the base sequence of polynucleotides 量子生物有限公司 2018-12-28 — — CN disclosed
CN-108686203-A Use the combination treatment of anti-hyaluronic acid agent and cancer target taxane 哈洛齐梅公司 2018-10-23 — — CN disclosed
CN-108135920-A Combination treatment 努卡那有限公司 2018-06-08 — — CN disclosed
CN-105264093-B Pyrophosphorolysis is sequenced 伊鲁米纳剑桥有限公司 2018-04-10 — — CN disclosed
CN-107835858-A Compositions, systems, and methods for sequencing polynucleotides using tethers anchored to polymerases adjacent to nanopores 亿明达股份有限公司 2018-03-23 — — CN disclosed
CN-106687574-A Compositions, systems and methods for detecting events using tethers anchored to or near nanoparticles 亿明达股份有限公司 2017-05-17 — — CN disclosed
CN-106574296-A A method and kit for determining the tissue or cell origin of DNA 耶路撒冷希伯来大学伊森姆研究发展公司 2017-04-19 — — CN disclosed
CN-102124018-A Unnatural polymerase substrates that can sustain enzymatic synthesis of double stranded nucleic acids from a nucleic acid template and methods of use LIFE TECHNOLOGIES 2011-07-13 — — CN disclosed
WO-2006003638-A2 NOVEL METHOD FOR LABELING NUCLEIC ACID IN A SEQUENCE-SPECIFIC MANNER, AND METHOD FOR DETECTING NUCLEIC ACID USING THE SAME NATIONAL INSTITUTE OF AGROBIOLOGICAL SCIENCES (JP) 2006-01-12 — — WO disclosed
CN-1007907-B Purification of Recombinant Human Interleukin-2 HOFFMANN LAROCHE & CO AG F (CH) 1990-05-09 — — CN disclosed
CN-85103306-A The purification of recombinant interleukin element-2 — 1987-05-27 — — CN disclosed
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