SCHEMBL6066494

SCHEMBL6066494

CCOC(=O)c1cc(OCC)c(Br)c(OCCc2ccc(Cl)cc2Cl)c1

nearest known ligand 0.54

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
F10 P00742 17/20 0.54
S1PR4 O95977 1/20 0.44
MAPT P10636 2/20 0.42
GAA P10253 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
GPR55 Q9Y2T6 1/20 0.42
NPC1 O15118 1/20 0.42
POLB P06746 1/20 0.42
TSHR P16473 1/20 0.42
RAB9A P51151 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
HSD17B10 Q99714 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6871677 0.91 F10 (0.47) F10S1PR4MAPTGAANPSR1
SCHEMBL6066445 0.90 F10 (0.54) F10S1PR4MAPTNPC1POLB
SCHEMBL6066475 0.89 F10 (0.56) F10S1PR4POLB
SCHEMBL6066669 0.88 F10 (0.58) F10S1PR4
SCHEMBL6864913 0.82 F10 (0.59) F10
SCHEMBL6066401 0.80 F10 (0.54) F10S1PR4MAPTNPC1POLB
SCHEMBL6066458 0.80 F10 (0.53) F10S1PR4MAPT
SCHEMBL6066759 0.80 F10 (0.56) F10
SCHEMBL289285 0.79 CA12 (0.55) MAPTNPC1TSHRHSD17B10
SCHEMBL6066603 0.79 NR4A2 (0.48) F10S1PR4MAPTNPC1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7067665-B2 Oxybenzamide derivatives useful for inhibiting factor Xa or Vlla SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2006-06-27 US disclosed
US-6953857-B2 Oxybenzamide derivatives useful for inhibiting factor Xa or viia AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2005-10-11 US disclosed
US-20050165058-A1 Oxybenzamide derivatives useful for inhibiting factor Xa or Vlla AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2005-07-28 US disclosed
EP-1349847-B1 OXYBENZAMIDES DERIVATIVES AS FACTOR XA INHIBITORS AVENTIS PHARMA GMBH (DE) 2005-04-20 EP disclosed
CN-1481376-A HYDROXYBENZAMIDE DERIVATIVES AS FACTOR XA INHIBITORS ���ĵ�˹ҩ��¹����޹�˾ 2004-03-10 CN disclosed
US-20020198195-A1 New oxybenzamide derivatives useful for inhibiting factor Xa or VIIa SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2002-12-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050165058-A1 Oxybenzamide derivatives useful for inhibiting factor Xa or Vlla F12, F11, F5 F10 7/4885S1PR4 3166/4885MAPT 4842/4885
US-20020198195-A1 New oxybenzamide derivatives useful for inhibiting factor Xa or VIIa F9, F11, F5 F10 8/4885S1PR4 2763/4885MAPT 4783/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.