SCHEMBL606714

SCHEMBL606714

N[C@@H](Cc1ccc(O)cc1)C(=O)OC(=O)[C@@H](N)Cc1cnc[nH]1

nearest known ligand 0.56

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.56
SLC7A5 Q01650 1/20 0.56
NLN Q9BYT8 3/20 0.49
LTA4H P09960 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1007042 0.88 CYP3A4 (0.61) CYP3A4SLC7A5NLNLTA4H
SCHEMBL163444 0.88 CYP3A4 (0.71) CYP3A4SLC7A5
SCHEMBL1537285 0.88 CYP3A4 (0.71) CYP3A4SLC7A5
Tyrosine SCHEMBL9243083 0.87 SLC7A5 (0.76) CYP3A4SLC7A5NLN
Hydrochloric Acid SCHEMBL28331180 0.86 CYP3A4 (0.69) CYP3A4SLC7A5
SCHEMBL162081 0.82 CYP3A4 (0.63) CYP3A4SLC7A5
SCHEMBL9082370 0.82 CYP3A4 (0.63) CYP3A4SLC7A5
SCHEMBL9083164 0.82 CYP3A4 (0.63) CYP3A4SLC7A5
SCHEMBL15911724 0.82 CYP3A4 (0.63) CYP3A4SLC7A5
SCHEMBL28328192 0.82 CYP3A4 (0.67) CYP3A4SLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104271595-A Proteins toxic to hemipteran insect species MONSANTO TECHNOLOGY LLC 2015-01-07 CN claimed
EP-1390074-A4 NOVEL COMPOSITIONS AND USES THEREFOR UNIV QUEENSLAND (AU) 2007-03-14 EP claimed
EP-1292615-B1 MODIFIED MORBILLIVIRUS V PROTEINS WYETH CORP (US) 2006-10-25 EP claimed
US-20040241177-A1 For producing antigen-primed antigen-presenting cells for eliciting a humoral and cellular immunity against target antigens; intracellular proteolytic degradation of second antigen is increased; immunogens; sustained release UNIQUEST PTY LTD (AU) 2004-12-02 US claimed
EP-1390074-A1 NOVEL COMPOSITIONS AND USES THEREFOR THE UNIVERSITY OF QUEENSLAND (AU) 2004-02-25 EP claimed
US-6664066-B2 Mutant measles virus V protein; gene expression and engineering WYETH HOLDINGS CORPORATION 2003-12-16 US claimed
US-20030206925-A1 MODIFIED MORBILLIVIRUS V PROTEINS WYETH HOLDINGS CORPORATION 2003-11-06 US claimed
WO-2002083181-A1 NOVEL COMPOSITIONS AND USES THEREFOR THE UNIVERSITY OF QUEENSLAND (AU) 2002-10-24 WO claimed
CN-117460418-A Non-dairy creamer composition 皇家戴维艾格伯茨有限公司 2024-01-26 CN disclosed
WO-2023121483-A1 IMMUNOSTIMULATORY COMPOSITIONS VICTORIA LINK LIMITED (NZ) 2023-06-29 WO disclosed
CN-114685681-A Application of HrpNECh protein in pharmacy for recognizing and activating multiple types of receptors and/or membrane proteins and signal pathways thereof 吴伯骥 2022-07-01 CN disclosed
CN-110869384-A Cell factory with improved delivery of iron-sulfur clusters 毒菌公司 2020-03-06 CN disclosed
US-20190336581-A1 IMMUNOSTIMULATORY COMPOSITIONS AND USES THEREFOR THE AUSTRALIAN NATIONAL UNIVERSITY (AU) 2019-11-07 US disclosed
US-20180305705-A1 CONSTRUCTS FOR GENE EXPRESSION ANALYSIS GENE STREAM PTY LTD (AU) 2018-10-25 US disclosed
EP-1373528-A1 NOVEL EXPRESSION VECTORS Gene Stream Pty Ltd. (AU) 2004-01-02 EP disclosed
US-6664066-B2 Mutant measles virus V protein; gene expression and engineering WYETH HOLDINGS CORPORATION 2003-12-16 US disclosed
US-20030206925-A1 MODIFIED MORBILLIVIRUS V PROTEINS WYETH HOLDINGS CORPORATION 2003-11-06 US disclosed
WO-2002083181-A1 NOVEL COMPOSITIONS AND USES THEREFOR THE UNIVERSITY OF QUEENSLAND (AU) 2002-10-24 WO disclosed
WO-2002072844-A1 NOVEL EXPRESSION VECTORS GENE STREAM PTY LTD (AU) 2002-09-19 WO disclosed
US-5399345-A His at position 52 is substituted with Ser, Arg, or Glu BOEHRINGER MANNHEIM, GMBH (DE) 1995-03-21 US disclosed