SCHEMBL606729

SCHEMBL606729

CC(C)C(=O)NCO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25514706 0.80 ALDH1A1 (0.44)
SCHEMBL5853497 0.80
SCHEMBL25964962 0.79 ALDH1A1 (0.45)
SCHEMBL12131751 0.79 USP2 (0.55)
SCHEMBL10447930 0.79 CYP2C19 (0.41)
SCHEMBL9226670 0.78
SCHEMBL12017871 0.78 ALDH1A1 (0.43)
SCHEMBL29209648 0.78
SCHEMBL21644459 0.78 ALDH1A1 (0.43)
(Isobutyrylamino)Acetic Acid SCHEMBL622544 0.78 ALDH1A1 (0.67)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113943234-A Preparation method of sulfonylphenylurea herbicide safener 常州大学 2022-01-18 CN claimed
CN-1277470-C Pesticide compositions ROHM & HAAS (US) 2006-10-04 CN claimed
CN-1196879-A Pesticide compositions ROHM & HAAS (US) 1998-10-28 CN claimed
CN-115490592-A Method for constructing 1, 4-diene drug molecular skeleton 南京工业大学 2022-12-20 CN disclosed
CN-113943234-A Preparation method of sulfonylphenylurea herbicide safener 常州大学 2022-01-18 CN disclosed
US-20190290645-A1 Aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquinoline derivatives, pharmaceutical compositions containing them, and their use in therapy AbbVie Deutschland GmbH & Co. KG (DE) 2019-09-26 US disclosed
US-20190290632-A1 Aminotetraline and aminoindane derivatives, pharmaceutical compositions containing them, and their use in therapy AbbVie Deutschland GmbH & Co. KG (DE) 2019-09-26 US disclosed
EP-3057958-B1 AMINOTETRALINE AND AMINOINDANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY ABBVIE DEUTSCHLAND (DE) 2019-05-01 EP disclosed
EP-2970215-B1 PYRROLIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY ABBVIE DEUTSCHLAND (DE) 2019-04-17 EP disclosed
EP-2814810-B1 ISOINDOLINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY ABBVIE DEUTSCHLAND (DE) 2018-12-19 EP disclosed
US-20170172993-A1 Aminotetraline and aminoindane derivatives, pharmaceutical compositions containing them, and their use in therapy ABBVIE INC. 2017-06-22 US disclosed
US-20080221195-A1 1,2-DIARYLACETYLENE DERIVATIVES OF ACYLTRYPTOPHANOLS BAYER SCHERING PHARMA AG (DE) 2008-09-11 US disclosed
CN-1816775-A Photosensitive resin composition CLARIANT INT LTD (JP) 2006-08-09 CN disclosed
CN-1806206-A Photosensitive resin composition AZ ELECTRONIC MATERIALS JAPAN (JP) 2006-07-19 CN disclosed
CN-1774671-A Photosensitive resin composition AZ ELECTRONIC MATERIAL JAPAN C (JP) 2006-05-17 CN disclosed
EP-0792869-B1 Azoamide compounds and their use as polymerization initiators WAKO PURE CHEM IND LTD (JP) 2002-05-22 EP disclosed
EP-0792869-A1 Azoamide compounds and their use as polymerization initiators WAKO PURE CHEMICAL INDUSTRIES, LTD (JP) 1997-09-03 EP disclosed
EP-0382213-B1 Biphenyl derivative, nerve cell degeneration repairing or protecting agent and process for preparing a phenyl derivative contained in the agent OTSUKA PHARMA CO LTD (JP) 1995-05-10 EP disclosed
US-5053548-A Containing hydroxy substituents; nervous system disorders OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) 1991-10-01 US disclosed
EP-0382213-A2 Biphenyl derivative, nerve cell degeneration repairing or protecting agent and process for preparing a phenyl derivative contained in the agent OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1990-08-16 EP disclosed