Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.52 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 2/20 | 0.44 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | AMPD3 | Q01432 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14502372 | 0.98 | MEN1 (0.57) | MEN1KMT2AMAPTATML3MBTL1 | |
| SCHEMBL7508348 | 0.98 | MEN1 (0.57) | MEN1KMT2AMAPTATML3MBTL1 | |
| SCHEMBL7510917 | 0.98 | MEN1 (0.57) | MEN1KMT2AMAPTATML3MBTL1 | |
| SCHEMBL10631549 | 0.98 | MEN1 (0.57) | MEN1KMT2AMAPTATML3MBTL1 | |
| SCHEMBL25189076 | 0.98 | MEN1 (0.57) | MEN1KMT2AMAPTATML3MBTL1 | |
| SCHEMBL7508728 | 0.94 | CYP4F2 (0.48) | MEN1KMT2AMAPTATML3MBTL1 | |
| SCHEMBL10001105 | 0.90 | MEN1 (0.54) | MEN1KMT2AMAPTATML3MBTL1 | |
| Malonic Acid SCHEMBL8372738 | 0.89 | MEN1 (0.54) | MEN1KMT2AMAPTATML3MBTL1 | |
| SCHEMBL10031336 | 0.86 | CYP4F2 (0.70) | MEN1KMT2AMAPTATML3MBTL1 | |
| SCHEMBL3145666 | 0.85 | MMP8 (0.48) | MEN1KMT2AMAPTATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110257434-A1 | PERTURBED MEMBRANE-BINDING COMPOUNDS AND METHODS OF USING THE SAME | APOSENSE LTD. (IL) | 2011-10-20 | — | — | US | disclosed |
| WO-2006100606-A2 | PREPARATION OF BETA-AMINO ACID PRECURSORS VIA INDIUM (III) MEDIATED MARKOVNIKOV ADDITION AND KNOEVENAGEL CONDENSATION | WARNER-LAMBERT COMPANY LLC (US) | 2006-09-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110257434-A1 | PERTURBED MEMBRANE-BINDING COMPOUNDS AND METHODS OF USING THE SAME | ANXA5, SELPLG, ANXA6 | MEN1 1808/4885KMT2A 4743/4885MAPT 3913/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.