Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8149306 | 0.86 | ALDH1A1 (0.54) | MAPTNPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL9661113 | 0.84 | NPC1 (0.53) | MAPTNPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL2098734 | 0.83 | NPC1 (0.59) | MAPTNPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL28226195 | 0.83 | NPC1 (0.59) | MAPTNPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL28189542 | 0.81 | NPC1 (0.57) | MAPTNPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL6958681 | 0.80 | NPC1 (0.56) | MAPTNPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL2036336 | 0.79 | NPC1 (0.54) | MAPTNPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL7068669 | 0.77 | KMT2A (0.57) | MAPTNPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL11648186 | 0.77 | MAPT (0.47) | MAPTNPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL5450997 | 0.76 | MEN1 (0.56) | MAPTNPC1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006100606-A2 | PREPARATION OF BETA-AMINO ACID PRECURSORS VIA INDIUM (III) MEDIATED MARKOVNIKOV ADDITION AND KNOEVENAGEL CONDENSATION | WARNER-LAMBERT COMPANY LLC (US) | 2006-09-28 | — | — | WO | disclosed |