Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 2/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25159581 | 0.85 | MEN1 (0.51) | MEN1KMT2ACTDSP1RAB9AL3MBTL1 | |
| SCHEMBL28319517 | 0.85 | MEN1 (0.51) | MEN1KMT2ACTDSP1RAB9AL3MBTL1 | |
| SCHEMBL27978308 | 0.83 | MEN1 (0.50) | MEN1KMT2ACTDSP1RAB9AL3MBTL1 | |
| SCHEMBL11311392 | 0.82 | MEN1 (0.49) | MEN1KMT2ACTDSP1RAB9AL3MBTL1 | |
| SCHEMBL31376543 | 0.82 | MEN1 (0.49) | MEN1KMT2ACTDSP1RAB9AL3MBTL1 | |
| SCHEMBL11311388 | 0.82 | MEN1 (0.49) | MEN1KMT2ACTDSP1RAB9AL3MBTL1 | |
| SCHEMBL13272157 | 0.81 | MEN1 (0.47) | MEN1KMT2ACTDSP1RAB9AL3MBTL1 | |
| SCHEMBL13250875 | 0.81 | MEN1 (0.47) | MEN1KMT2ACTDSP1RAB9AL3MBTL1 | |
| SCHEMBL24575249 | 0.80 | MEN1 (0.50) | MEN1KMT2ACTDSP1RAB9AL3MBTL1 | |
| SCHEMBL11988773 | 0.80 | RAB9A (0.47) | MEN1KMT2ACTDSP1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006100606-A2 | PREPARATION OF BETA-AMINO ACID PRECURSORS VIA INDIUM (III) MEDIATED MARKOVNIKOV ADDITION AND KNOEVENAGEL CONDENSATION | WARNER-LAMBERT COMPANY LLC (US) | 2006-09-28 | — | — | WO | disclosed |