Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 19/20 | 0.44 |
| ▸ | HTR2A | P28223 | 18/20 | 0.44 |
| ▸ | HTR2B | P41595 | 8/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.42 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6068577 | 0.83 | SMPD3 (0.31) | HTR2CHTR2AHTR2BSMPD3 | |
| SCHEMBL6068716 | 0.81 | CHRM2 (0.35) | HTR1AADRA2ASMPD3 | |
| SCHEMBL5160540 | 0.79 | HTR2C (0.47) | HTR2CHTR2AHTR2BHTR1AADRA2A | |
| SCHEMBL6068625 | 0.76 | — | — | |
| SCHEMBL6068957 | 0.75 | — | — | |
| SCHEMBL5423587 | 0.74 | HTR2C (0.43) | HTR2CHTR2AHTR2BHTR1AADRA2A | |
| SCHEMBL6068568 | 0.74 | — | — | |
| SCHEMBL6068970 | 0.72 | — | — | |
| SCHEMBL6068698 | 0.72 | — | — | |
| SCHEMBL6068953 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7091350-B2 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | L'OREAL (FR) | 2006-08-15 | — | — | US | disclosed |