Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 20/20 | 0.43 |
| ▸ | HTR2A | P28223 | 18/20 | 0.43 |
| ▸ | HTR2B | P41595 | 8/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5160540 | 0.78 | HTR2C (0.47) | HTR2CHTR2AHTR2BHTR1AADRA2A | |
| SCHEMBL4804121 | 0.74 | CYP1A2 (0.36) | — | |
| SCHEMBL6068346 | 0.74 | HTR2C (0.44) | HTR2CHTR2AHTR2BHTR1AADRA2A | |
| SCHEMBL5423579 | 0.74 | — | — | |
| SCHEMBL5424153 | 0.71 | LMNA (0.35) | — | |
| SCHEMBL14445262 | 0.71 | GAA (0.40) | — | |
| SCHEMBL5427359 | 0.71 | CNR1 (0.34) | — | |
| SCHEMBL5420273 | 0.71 | LRRK2 (0.38) | — | |
| Hydrochloric Acid SCHEMBL5427295 | 0.70 | LRRK2 (0.37) | — | |
| SCHEMBL5441226 | 0.70 | LMNA (0.34) | HTR2CHTR2AHTR2BHTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7250063-B2 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | L'OREAL (FR) | 2007-07-31 | — | — | US | disclosed |