⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3779898 | 0.69 | — | — | |
| SCHEMBL7490993 | 0.69 | — | — | |
| SCHEMBL11198716 | 0.65 | ALDH1A1 (0.39) | — | |
| Trimethylammonium SCHEMBL9185431 | 0.55 | ALDH1A1 (0.30) | — | |
| Trimethylammonium SCHEMBL160656 | 0.55 | — | — | |
| N,N-Dimethylethanaminium SCHEMBL16338 | 0.51 | — | — | |
| N,N-Dimethylethanaminium SCHEMBL2146567 | 0.51 | TSHR (0.36) | — | |
| SCHEMBL98977 | 0.51 | — | — | |
| SCHEMBL352063 | 0.51 | — | — | |
| N,N-Dimethylethanaminium SCHEMBL352062 | 0.51 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114380883-B | Aminoalkoxy tripterine derivative, preparation method and application | 中国人民解放军空军军医大学 | 2023-06-30 | — | — | CN | claimed |
| EP-0138464-B1 | 2-AMINO-5-HYDROXY-4-METHYLPYRIMIDINE DERIVATIVES | PFIZER INC. (US) | 1989-11-15 | — | — | EP | claimed |
| EP-0222253-B1 | SUBSTITUTED 5-AMINO-1-ARYL-PYRAZOLES | BAYER AG (DE) | 1989-04-05 | — | — | EP | claimed |
| US-4725677-A | USING PHOSPHINE DERIVATIVE | BIOSYNTECH GMBH (DE) | 1988-02-16 | — | — | US | claimed |
| EP-0137351-A2 | Process for the enantioselective préparation of acyclic alpha-alkylated alpha-aminecarboxylic acids | Degussa Aktiengesellschaft (DE) | 1985-04-17 | — | — | EP | claimed |
| CN-114380883-B | Aminoalkoxy tripterine derivative, preparation method and application | 中国人民解放军空军军医大学 | 2023-06-30 | — | — | CN | disclosed |
| EP-3851444-A1 | INHIBITORS OF GLUCOCORTICOID RECEPTOR | Oric Pharmaceuticals, Inc. (US) | 2021-07-21 | — | — | EP | disclosed |
| US-20210128561-A1 | MRGX Receptor Antagonists | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2021-05-06 | — | — | US | disclosed |
| US-10093657-B2 | Inhibitors of bruton's tyrosine kinase | HOFFMANN-LA ROCHE INC. (US) | 2018-10-09 | — | — | US | disclosed |
| US-20170183327-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | CHUGAI PHARMACEUTICAL CO. (JP) | 2017-06-29 | — | — | US | disclosed |
| US-20160361356-A1 | METHODS, COMPOSITIONS AND ARTICLES OF MANUFACTURE FOR ENHANCING SURVIVABILITY OF CELLS, TISSUES, ORGANS, AND ORGANISMS | FRED HUTCHINSON CANCER RESEARCH CENTER | 2016-12-15 | — | — | US | disclosed |
| US-8822535-B2 | Methods, compositions and articles of manufacture for enhancing survivability of cells, tissues, organs, and organisms | FRED HUTCHINSON CANCER RESEARCH CENTER (US) | 2014-09-02 | — | — | US | disclosed |
| EP-0138464-B1 | 2-AMINO-5-HYDROXY-4-METHYLPYRIMIDINE DERIVATIVES | PFIZER INC. (US) | 1989-11-15 | — | — | EP | disclosed |
| EP-0304190-A1 | (Arylsulphonyl)nitromethanes, process for their preparation and use in pharmaceutical compositions | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-02-22 | — | — | EP | disclosed |
| EP-0299209-A2 | Pyrazolopyridine compound and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-01-18 | — | — | EP | disclosed |
| EP-0286242-A2 | Ethanolamine derivates, processes for their preparation and pharmaceutical compositions containing them | GLAXO GROUP LIMITED (GB) | 1988-10-12 | — | — | EP | disclosed |
| US-4767769-A | HISTAMINE-H2 ANTAGONISTS | THE BOOTS COMPANY PLC (GB) | 1988-08-30 | — | — | US | disclosed |
| EP-0112524-B1 | TRICHLOROACRYLOYL OXIME DERIVATIVES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-05-28 | — | — | EP | disclosed |
| EP-0112524-A1 | Trichloroacryloyl oxime derivatives | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1984-07-04 | — | — | EP | disclosed |
| EP-0097072-A1 | Derivatives of benzylsulfinyl acetamides, their therapeutic use and process for their preparation | LABORATOIRE L. LAFON Société anonyme dite: (FR) | 1983-12-28 | — | — | EP | disclosed |