Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6068921 | 0.91 | MAPT (0.33) | MAPT | |
| SCHEMBL6068644 | 0.86 | — | — | |
| SCHEMBL6068924 | 0.79 | TDP1 (0.31) | — | |
| SCHEMBL6068802 | 0.79 | CYP2D6 (0.33) | MAPTCYP2D6CYP1A2 | |
| SCHEMBL6068602 | 0.78 | — | — | |
| SCHEMBL5416781 | 0.78 | KDM4E (0.35) | MAPTCYP2D6CYP1A2 | |
| SCHEMBL6068845 | 0.78 | CYP2D6 (0.32) | MAPTCYP2D6CYP1A2 | |
| SCHEMBL6068734 | 0.77 | KMO (0.31) | — | |
| SCHEMBL14445306 | 0.76 | KDM4E (0.37) | MAPTCYP1A2 | |
| SCHEMBL6068794 | 0.76 | KCNH2 (0.33) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7091350-B2 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | L'OREAL (FR) | 2006-08-15 | — | — | US | disclosed |