Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | MPO | P05164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6068455 | 0.91 | TDP1 (0.33) | TDP1ALDH1A1LMNAALOX15LRRK2 | |
| SCHEMBL6068924 | 0.87 | TDP1 (0.31) | TDP1ALDH1A1LMNAALOX15MPO | |
| SCHEMBL6068724 | 0.84 | TDP1 (0.33) | TDP1ALDH1A1LMNAALOX15LRRK2 | |
| SCHEMBL6068975 | 0.83 | MEN1 (0.31) | — | |
| SCHEMBL15651733 | 0.81 | ALDH1A1 (0.35) | TDP1ALDH1A1LMNAALOX15LRRK2 | |
| SCHEMBL6068644 | 0.75 | — | — | |
| SCHEMBL6068513 | 0.75 | ABL1 (0.30) | — | |
| SCHEMBL33797 | 0.75 | ALDH1A1 (0.37) | TDP1ALDH1A1LMNAALOX15LRRK2 | |
| SCHEMBL6068670 | 0.75 | MEN1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL6282164 | 0.74 | ALDH1A1 (0.36) | TDP1ALDH1A1LMNAALOX15LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7091350-B2 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | L'OREAL (FR) | 2006-08-15 | — | — | US | disclosed |