Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 14/20 | 0.73 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5903476 | 1.00 | SLC6A3 (0.73) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL6070325 | 1.00 | SLC6A3 (0.73) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL9130358 | 0.85 | SLC6A3 (0.56) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL9129313 | 0.83 | SLC6A3 (0.54) | SLC6A3 | |
| SCHEMBL1565214 | 0.80 | SLC6A3 (0.69) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL15846301 | 0.79 | SLC6A3 (0.70) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL1565823 | 0.79 | SLC6A3 (0.70) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL4627138 | 0.77 | SLC6A3 (0.65) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL9131842 | 0.77 | SLC6A3 (0.53) | SLC6A3 | |
| SCHEMBL2642544 | 0.75 | SLC6A3 (0.50) | SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7026516-B2 | Compounds with high monoamine transporter affinity | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2006-04-11 | — | — | US | disclosed |