Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 17/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 15/20 | 0.43 |
| ▸ | RBP4 | P02753 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL607935 | 0.83 | HCRTR1 (0.49) | HCRTR2HCRTR1 | |
| SCHEMBL10121575 | 0.82 | HCRTR2 (0.53) | HCRTR2HCRTR1 | |
| SCHEMBL608692 | 0.82 | HCRTR2 (0.53) | HCRTR2HCRTR1 | |
| SCHEMBL10121619 | 0.82 | HCRTR2 (0.53) | HCRTR2HCRTR1 | |
| SCHEMBL609561 | 0.81 | HCRTR2 (0.63) | HCRTR2HCRTR1 | |
| SCHEMBL10121570 | 0.80 | HCRTR2 (0.55) | HCRTR2HCRTR1 | |
| SCHEMBL7861881 | 0.79 | HCRTR1 (0.44) | HCRTR2HCRTR1 | |
| SCHEMBL607971 | 0.79 | HCRTR1 (0.44) | HCRTR2HCRTR1 | |
| SCHEMBL608678 | 0.78 | HCRTR1 (0.40) | HCRTR2HCRTR1RBP4 | |
| SCHEMBL608476 | 0.78 | HCRTR1 (0.45) | HCRTR2HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120040991-A1 | 3-AZABICYCLO [4.1.0] HEPTANES USED AS OREXIN ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2012-02-16 | — | — | US | disclosed |
| US-20120040991-A1 | 3-AZABICYCLO [4.1.0] HEPTANES USED AS OREXIN ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2012-02-16 | — | — | US | disclosed |
| WO-2010122151-A1 | 3 -AZABICYCLO [4.1.0] HEPTANES USED AS OREXIN ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2010-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040991-A1 | 3-AZABICYCLO [4.1.0] HEPTANES USED AS OREXIN ANTAGONISTS | HCRTR2, HCRTR1, NPY2R | HCRTR2 1/4885HCRTR1 2/4885RBP4 608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.