Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 2/20 | 0.41 |
| ▸ | RXRB | P28702 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6258640 | 0.85 | SMN1; SMN2 (0.46) | SMN1; SMN2CYP1A2CYP3A4CYP2C19GLA | |
| SCHEMBL1258872 | 0.85 | CYP1A2 (0.50) | SMN1; SMN2CYP1A2CYP3A4CYP2C19GLA | |
| SCHEMBL1257818 | 0.83 | SMN1; SMN2 (0.54) | SMN1; SMN2CYP1A2CYP3A4CYP2C19GLA | |
| Ammonia Solution, Strong SCHEMBL28714250 | 0.82 | SMN1; SMN2 (0.53) | SMN1; SMN2CYP1A2CYP3A4CYP2C19GLA | |
| SCHEMBL28725005 | 0.78 | AKR1B1 (0.57) | SMN1; SMN2CYP1A2CYP3A4CYP2C19GLA | |
| SCHEMBL128869 | 0.78 | SMN1; SMN2 (0.50) | SMN1; SMN2CYP1A2CYP3A4CYP2C19GLA | |
| SCHEMBL11741944 | 0.78 | SRC (0.52) | SMN1; SMN2CYP1A2CYP3A4CYP2C19GLA | |
| SCHEMBL11443283 | 0.77 | CYP1A2 (0.44) | SMN1; SMN2CYP1A2CYP3A4CYP2C19GLA | |
| SCHEMBL7911305 | 0.76 | PTGS2 (0.56) | SMN1; SMN2CYP1A2CYP3A4CYP2C19GLA | |
| SCHEMBL6384650 | 0.76 | SMN1; SMN2 (0.47) | SMN1; SMN2CYP1A2CYP3A4CYP2C19GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170255100-A1 | DRY FILM STRUCTURE | FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. | 2017-09-07 | — | — | US | disclosed |
| US-7034055-B1 | 2-aminoindane analogs | PRESCIENT NEUROPHARMA INC. (CA) | 2006-04-25 | — | — | US | disclosed |
| EP-1194400-A1 | 2-AMINOINDANE ANALOGS | Prescient Neuropharma Inc. (CA) | 2002-04-10 | — | — | EP | disclosed |
| WO-2001002342-A1 | 2-AMINOINDANE ANALOGS | IGT PHARMA INC. (CA) | 2001-01-11 | — | — | WO | disclosed |