Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6071091 | 0.89 | ADORA1 (0.49) | ADORA3ADORA2AADORA2BADORA1MEN1 | |
| SCHEMBL5398636 | 0.81 | ADORA1 (0.57) | ADORA3ADORA2AADORA2BADORA1MEN1 | |
| SCHEMBL5388721 | 0.81 | ADORA1 (0.57) | ADORA3ADORA2AADORA2BADORA1MEN1 | |
| SCHEMBL5401453 | 0.79 | ADORA3 (0.49) | ADORA3ADORA2AADORA2BADORA1MEN1 | |
| SCHEMBL5392511 | 0.76 | ADORA3 (0.56) | ADORA3ADORA2AADORA2BADORA1MEN1 | |
| SCHEMBL5394909 | 0.76 | ADORA3 (0.56) | ADORA3ADORA2AADORA2BADORA1MEN1 | |
| SCHEMBL5390598 | 0.75 | ADORA2A (0.74) | ADORA3ADORA2AADORA2BADORA1MEN1 | |
| SCHEMBL5391713 | 0.75 | ADORA2A (0.74) | ADORA3ADORA2AADORA2BADORA1MEN1 | |
| SCHEMBL6070623 | 0.73 | ADORA1 (0.51) | ADORA3ADORA2AADORA2BADORA1MEN1 | |
| SCHEMBL20180316 | 0.72 | ADORA3 (0.67) | ADORA3ADORA2AADORA2BADORA1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2006516641-A | — | — | 2006-07-06 | — | — | JP | claimed |
| EP-1590359-A2 | PARTIAL AND FULL AGONISTS OF A sb 1 /sb ADENOSINE RECEPTORS | CV Therapeutics Inc. (US) | 2005-11-02 | — | — | EP | claimed |
| WO-2004069185-A2 | PARTIAL AND FULL AGONISTS OF A1 ADENOSINE RECEPTORS | CV THERAPEUTICS INC. (US) | 2004-08-19 | — | — | WO | claimed |