⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30594257 | 0.79 | MAOB (0.39) | — | |
| SCHEMBL27411282 | 0.75 | POLB (0.41) | — | |
| SCHEMBL27490806 | 0.75 | CHRNB4 (0.39) | — | |
| SCHEMBL28896993 | 0.74 | CLK4 (0.44) | — | |
| SCHEMBL570014 | 0.74 | CHRNB4 (0.42) | — | |
| SCHEMBL24035501 | 0.70 | MKNK1 (0.37) | — | |
| SCHEMBL8191317 | 0.70 | NOTUM (0.44) | — | |
| SCHEMBL27499092 | 0.68 | NQO2 (0.46) | — | |
| SCHEMBL8585311 | 0.67 | ALDH1A1 (0.32) | — | |
| SCHEMBL10343777 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060116400-A1 | Oxazolidinone and/or isoxazoline derivatives as antibacterial agents | ASTRAZENECA AB (SE) | 2006-06-01 | — | — | US | disclosed |
| EP-1567532-A1 | OXAZOLIDINONE AND / OR ISOXAZOLINE DERIVATIVES AS ANTIBACTERIAL AGENTS | Astrazeneca AB (SE) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004048392-A1 | OXAZOLIDINONE AND / OR ISOXAZOLINE DERIVATIVES AS ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2004-06-10 | — | — | WO | disclosed |