Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 19/20 | 1.00 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.68 |
| ▸ | HRH1 | P35367 | 3/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5093837 | 0.93 | HRH3 (0.91) | HRH3MCHR1 | |
| SCHEMBL5100461 | 0.93 | HRH3 (1.00) | HRH3MCHR1 | |
| SCHEMBL6071736 | 0.86 | HRH3 (1.00) | HRH3HRH1 | |
| SCHEMBL6070800 | 0.85 | HRH3 (0.74) | HRH3HRH1 | |
| SCHEMBL6070778 | 0.85 | HRH3 (0.74) | HRH3HRH1 | |
| SCHEMBL14320109 | 0.85 | HRH3 (0.81) | HRH3HRH1 | |
| Hydrochloric Acid SCHEMBL6070934 | 0.85 | HRH3 (0.73) | HRH3HRH1 | |
| SCHEMBL14287764 | 0.84 | HRH3 (0.73) | HRH3HRH1 | |
| SCHEMBL6071051 | 0.84 | HRH3 (0.72) | HRH3HRH1 | |
| SCHEMBL6071740 | 0.84 | HRH3 (0.76) | HRH3HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060089347-A1 | Substituted azepines as histamine h3 receptor antagonists, preparation and therapeutic uses | ELI LILLY AND COMPANY (US) | 2006-04-27 | — | — | US | disclosed |
| WO-2004035544-A1 | BENZO[D]AZEPINE DERIVATIVES FOR THE TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | GLAXO GROUP LIMITED (GB) | 2004-04-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060089347-A1 | Substituted azepines as histamine h3 receptor antagonists, preparation and therapeutic uses | HRH3, HRH4, HRH2 | HRH3 1/4885MCHR1 69/4885HRH1 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.