Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.62 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | KIF11 | P52732 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL28007804 | 0.95 | CES2 (0.69) | CES2SRD5A2LMNAMAOBKCNK3 | |
| SCHEMBL27621589 | 0.93 | CES2 (0.71) | CES2SRD5A2LMNAMAOBPTGS1 | |
| SCHEMBL171684 | 0.93 | CES2 (0.71) | CES2SRD5A2LMNAMAOBPTGS1 | |
| Water SCHEMBL28050254 | 0.91 | CES2 (0.69) | CES2SRD5A2LMNAMAOBPTGS1 | |
| Hydrochloric Acid SCHEMBL4372373 | 0.91 | CES2 (0.69) | CES2SRD5A2LMNAMAOBPTGS1 | |
| Hydrochloric Acid SCHEMBL1267321 | 0.91 | CES2 (0.69) | CES2SRD5A2LMNAMAOBPTGS1 | |
| Acetic Acid SCHEMBL10340449 | 0.90 | CES2 (0.62) | CES2SRD5A2LMNAMAOBKCNK3 | |
| Trifluoroacetic Acid SCHEMBL10277408 | 0.87 | PARP1 (0.59) | PARP1KIF11POLB | |
| Trifluoroacetic Acid SCHEMBL29713373 | 0.87 | PARP1 (0.59) | PARP1KIF11POLB | |
| Formic Acid SCHEMBL29537369 | 0.86 | CES2 (0.62) | CES2SRD5A2LMNAMAOBPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060241149-A1 | Chemical compounds | ADAMS JERRY L | 2006-10-26 | — | — | US | disclosed |
| EP-1581514-A2 | CHEMICAL COMPOUNDS | SmithKline Beecham Corporation (US) | 2005-10-05 | — | — | EP | disclosed |
| WO-2004043379-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060241149-A1 | Chemical compounds | CHKB, MAP3K20, MAP3K6 | CES2 398/4885SRD5A2 2103/4885LMNA 2570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.