Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 16/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5764131 | 0.84 | CCR4 (1.00) | CCR4 | |
| SCHEMBL5764308 | 0.83 | CCR4 (0.80) | CCR4CCR5 | |
| SCHEMBL5764800 | 0.82 | CCR4 (0.79) | CCR4CCR5 | |
| SCHEMBL5765776 | 0.80 | CCR4 (0.67) | CCR4MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL1731222 | 0.74 | CCR4 (1.00) | CCR4 | |
| SCHEMBL29369177 | 0.74 | CCR4 (1.00) | CCR4 | |
| SCHEMBL5113238 | 0.73 | CCR5 (0.70) | CCR4MEN1KMT2AGAACCR5 | |
| SCHEMBL6180658 | 0.71 | CCR4 (0.69) | CCR4MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL1732411 | 0.71 | CCR4 (0.69) | CCR4MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL1732073 | 0.70 | CCR4 (0.79) | CCR4MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060128723-A1 | Sulptionamide compounds that modulate chemokine receptor activity (CCR4) | ASTRAZENECA AB (SE) | 2006-06-15 | — | — | US | claimed |
| US-20060128723-A1 | Sulptionamide compounds that modulate chemokine receptor activity (CCR4) | ASTRAZENECA AB (SE) | 2006-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128723-A1 | Sulptionamide compounds that modulate chemokine receptor activity (CCR4) | CCR4, CCR3, CCR1 | CCR4 1/4885MEN1 4630/4885KMT2A 2465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.