Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31444388 | 1.00 | KDM1A (0.42) | KDM1ANR1H2NR1H3STSMEN1 | |
| SCHEMBL18642718 | 0.82 | NR1H2 (0.53) | KDM1ANR1H2NR1H3GRIN2BGRIN2C | |
| SCHEMBL28815574 | 0.82 | NR1H2 (0.53) | KDM1ANR1H2NR1H3GRIN2BGRIN2C | |
| SCHEMBL16004573 | 0.82 | NR1H2 (0.53) | KDM1ANR1H2NR1H3GRIN2BGRIN2C | |
| SCHEMBL19462823 | 0.80 | MEN1 (0.48) | NR1H2NR1H3STSMEN1KMT2A | |
| SCHEMBL19459203 | 0.80 | MEN1 (0.48) | NR1H2NR1H3STSMEN1KMT2A | |
| SCHEMBL653342 | 0.74 | STS (0.47) | KDM1ASTSMEN1KMT2AHDAC1 | |
| SCHEMBL22300965 | 0.74 | RORC (0.46) | NR1H2NR1H3GRIN2BGRIN2CJAK3 | |
| SCHEMBL22300220 | 0.74 | USP30 (0.42) | NR1H2NR1H3HCRTR1HCRTR2GRIN2B | |
| SCHEMBL16797988 | 0.74 | HCRTR1 (0.63) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060160794-A1 | Tachykinin receptor antagonists | ELI LILLY AND COMPANY | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160794-A1 | Tachykinin receptor antagonists | TACR1, TACR2, PROKR1 | KDM1A 1400/4885NR1H2 1535/4885NR1H3 1651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.