Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | CD38 | P28907 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488488 | 0.86 | TAAR1 (0.39) | TAAR1GAANOTUMP2RX7BACE1 | |
| SCHEMBL1358925 | 0.82 | NOTUM (0.42) | TAAR1GAACYP3A4MAPK1NOTUM | |
| SCHEMBL616685 | 0.82 | TAAR1 (0.41) | TAAR1GAANOTUMBACE1CNR1 | |
| SCHEMBL11677898 | 0.80 | NOTUM (0.47) | TAAR1CYP3A4MAPK1NOTUMMAPT | |
| SCHEMBL1167603 | 0.78 | P2RX7 (0.43) | TAAR1GAACYP3A4P2RX7NR4A2 | |
| SCHEMBL29705432 | 0.78 | TAAR1 (0.38) | TAAR1GAACYP3A4MAPK1BACE1 | |
| SCHEMBL18585398 | 0.78 | TAAR1 (0.34) | TAAR1GAANR4A2KDM4ECYP1A2 | |
| SCHEMBL27215165 | 0.78 | TAAR1 (0.38) | TAAR1GAACYP3A4MAPK1BACE1 | |
| SCHEMBL4120436 | 0.77 | TAAR1 (0.36) | TAAR1GAACYP3A4MAPK1P2RX7 | |
| SCHEMBL6072548 | 0.77 | TAAR1 (0.36) | TAAR1GAACYP3A4MAPK1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006062477-A1 | CHEMICAL PROCESS | ASTRAZENECA AB (SE) | 2006-06-15 | — | — | WO | disclosed |