SCHEMBL6072747

SCHEMBL6072747

CCCCCCCCCCCCCCCCc1ccncc1C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM6B O15054 2/20 0.51
KDM4C Q9H3R0 2/20 0.51
GABRP O00591 2/20 0.49
GABRD O14764 2/20 0.49
GABRA1 P14867 2/20 0.49
GABRB1 P18505 2/20 0.49
GABRG2 P18507 2/20 0.49
GABRB3 P28472 2/20 0.49
GABRA5 P31644 2/20 0.49
GABRA3 P34903 2/20 0.49
GABRA2 P47869 2/20 0.49
GABRB2 P47870 2/20 0.49
GABRA4 P48169 2/20 0.49
GABRE P78334 2/20 0.49
GABRA6 Q16445 2/20 0.49
GABRG1 Q8N1C3 2/20 0.49
GABRG3 Q99928 2/20 0.49
GABRQ Q9UN88 2/20 0.49
PTGDR2 Q9Y5Y4 1/20 0.48
KAT8 Q9H7Z6 4/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5002411 1.00 KDM6B (0.51) KDM6BKDM4CGABRPGABRDGABRA1
SCHEMBL5002870 1.00 KDM6B (0.51) KDM6BKDM4CGABRPGABRDGABRA1
SCHEMBL4998464 1.00 KDM6B (0.51) KDM6BKDM4CGABRPGABRDGABRA1
SCHEMBL4998341 1.00 KDM6B (0.51) KDM6BKDM4CGABRPGABRDGABRA1
SCHEMBL4005290 0.94 GABRP (0.55) KDM6BKDM4CGABRPGABRDGABRA1
SCHEMBL3122447 0.88 KDM4C (0.55) KDM6BKDM4CGABRPGABRDGABRA1
SCHEMBL258369 0.87 KDM4C (0.51) KDM6BKDM4CGABRPGABRDGABRA1
SCHEMBL9879956 0.86 PTGDR2 (0.45) KDM6BKDM4CPTGDR2KAT8PPARA
SCHEMBL27449213 0.86 KDM4C (0.56) KDM6BKDM4CGABRPGABRDGABRA1
Hydrochloric Acid SCHEMBL5739434 0.85 KDM4C (0.50) KDM6BKDM4CGABRPGABRDGABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8557752-B2 Lubricating compositions AFTON CHEMICAL CORPORATION (US) 2013-10-15 US disclosed
US-20060217273-A1 Lubricating compositions AFTON CHEMICAL CORPORATION 2006-09-28 US disclosed