Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.38 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6073346 | 0.90 | MAPT (0.40) | ALDH1A1CYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL6072885 | 0.88 | CETP (0.39) | ALDH1A1CYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL6072966 | 0.84 | ALDH1A1 (0.37) | ALDH1A1CYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL6072783 | 0.78 | MAPT (0.39) | ALDH1A1CYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL6072746 | 0.76 | CETP (0.48) | ALDH1A1CYP1A2CYP2C9CYP2C19HPGD | |
| SCHEMBL6072901 | 0.73 | CETP (0.43) | ALDH1A1MAPTHPGDGAAPOLB | |
| SCHEMBL6072846 | 0.73 | CETP (0.50) | CYP1A2CYP2C9CYP2C19POLBCETP | |
| SCHEMBL4520334 | 0.70 | CXCR5 (0.43) | ALDH1A1CYP1A2CYP2C9CYP2C19HPGD | |
| SCHEMBL6072911 | 0.70 | CETP (0.47) | ALDH1A1MAPTHPGDPOLBCETP | |
| SCHEMBL9704892 | 0.70 | MAPT (0.46) | ALDH1A1CYP1A2CYP2C19MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006032987-A1 | INDOLINE COMPOUNDS AND THEIR USE IN THE TREATMENT OF ARTERIOSCLEROSIS | PFIZER PRODUCTS INC. (US) | 2006-03-30 | — | — | WO | disclosed |