Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.43 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10563196 | 0.84 | SMN1; SMN2 (0.49) | SMN1; SMN2NPC1RAB9AHTR2CCYP2C19 | |
| SCHEMBL12480315 | 0.76 | SMN1; SMN2 (0.60) | SMN1; SMN2NPC1RAB9AHTR2CCYP2C19 | |
| SCHEMBL3841510 | 0.76 | SMN1; SMN2 (0.60) | SMN1; SMN2NPC1RAB9AHTR2CCYP2C19 | |
| SCHEMBL3614635 | 0.75 | SMN1; SMN2 (0.68) | SMN1; SMN2NPC1RAB9ACYP2C19KMT2A | |
| SCHEMBL3529765 | 0.75 | SMN1; SMN2 (0.68) | SMN1; SMN2NPC1RAB9ACYP2C19KMT2A | |
| SCHEMBL3788614 | 0.75 | SMN1; SMN2 (0.68) | SMN1; SMN2NPC1RAB9ACYP2C19KMT2A | |
| SCHEMBL2896415 | 0.75 | SMN1; SMN2 (0.76) | SMN1; SMN2NPC1RAB9ACYP2C19KMT2A | |
| SCHEMBL30609918 | 0.73 | SMN1; SMN2 (0.47) | SMN1; SMN2NPC1RAB9AHTR2CCYP2C19 | |
| SCHEMBL4504921 | 0.73 | SMN1; SMN2 (0.60) | SMN1; SMN2NPC1RAB9AHTR2CCYP2C19 | |
| SCHEMBL25035422 | 0.72 | SMN1; SMN2 (0.59) | SMN1; SMN2NPC1RAB9ACYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006011035-A1 | NOVEL DIPEPTIDYL PEPTIDASE IV INHIBITORS; PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LTD. (US) | 2006-02-02 | — | — | WO | claimed |
| WO-2006011035-A1 | NOVEL DIPEPTIDYL PEPTIDASE IV INHIBITORS; PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LTD. (US) | 2006-02-02 | — | — | WO | disclosed |