Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 19/20 | 0.81 |
| ▸ | PPARG | P37231 | 17/20 | 0.81 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13717685 | 0.93 | PPARA (0.87) | PPARAPPARGCYP2C9KCNH2 | |
| SCHEMBL13720248 | 0.93 | PPARA (0.84) | PPARAPPARGCYP2C9KCNH2 | |
| SCHEMBL13717638 | 0.92 | PPARA (0.79) | PPARAPPARGCYP2C9KCNH2 | |
| SCHEMBL13718342 | 0.92 | PPARA (0.79) | PPARAPPARGCYP2C9KCNH2 | |
| SCHEMBL6073227 | 0.91 | PPARA (0.90) | PPARAPPARGCYP2C9KCNH2 | |
| SCHEMBL13717822 | 0.91 | PPARA (0.78) | PPARAPPARGCYP2C9KCNH2 | |
| SCHEMBL13718411 | 0.90 | PPARA (0.77) | PPARAPPARG | |
| SCHEMBL13717942 | 0.90 | PPARA (0.77) | PPARAPPARGCYP2C9KCNH2 | |
| Muraglitazar SCHEMBL676469 | 0.90 | PPARA (1.00) | PPARAPPARGCYP2C9KCNH2 | |
| SCHEMBL13717855 | 0.90 | PPARA (0.75) | PPARAPPARGCYP2C9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006117743-A1 | SUBSTITUTED AROMATIC COMPOUNDS AS ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |