Vitexin

Vitexin

SCHEMBL6073075

O=C(O)c1cc(O)c(O)c(O)c1.O=c1cc(-c2ccc(O)cc2)oc2c([C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c(O)cc(O)c12

nearest known ligand 0.82

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 5/20 0.82
CYP1A2 P05177 1/20 0.82
GAA P10253 5/20 0.69
KDM4E B2RXH2 5/20 0.69
POLB P06746 4/20 0.69
APEX1 P27695 4/20 0.69
MEN1 O00255 4/20 0.69
KMT2A Q03164 4/20 0.69
TDP1 Q9NUW8 3/20 0.69
ALDH1A1 P00352 2/20 0.69
MAPT P10636 2/20 0.69
THRB P10828 1/20 0.69
NTSR1 P30989 1/20 0.66
RECQL P46063 1/20 0.66
SYNJ2 O15056 1/20 0.57
AKR1B1 P15121 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.51
SLCO2B1 O94956 1/20 0.51
TNF P01375 1/20 0.51
XDH P47989 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Vitexin SCHEMBL2741236 0.91 L3MBTL1 (1.00) L3MBTL1CYP1A2GAAKDM4EPOLB
Vitexin SCHEMBL29572351 0.91 L3MBTL1 (1.00) L3MBTL1CYP1A2GAAKDM4EPOLB
Vitexin SCHEMBL25277 0.91 L3MBTL1 (1.00) L3MBTL1CYP1A2GAAKDM4EPOLB
Vitexin SCHEMBL10013309 0.91 L3MBTL1 (1.00) L3MBTL1CYP1A2GAAKDM4EPOLB
Vitexin SCHEMBL4469474 0.91 L3MBTL1 (1.00) L3MBTL1CYP1A2GAAKDM4EPOLB
Vitexin SCHEMBL10307510 0.91 L3MBTL1 (1.00) L3MBTL1CYP1A2GAAKDM4EPOLB
SCHEMBL10307503 0.86 L3MBTL1 (0.81) L3MBTL1CYP1A2GAAKDM4EPOLB
Vitexin SCHEMBL18585986 0.83 L3MBTL1 (0.81) L3MBTL1CYP1A2GAAKDM4EPOLB
Orientin SCHEMBL25942 0.82 L3MBTL1 (1.00) L3MBTL1CYP1A2GAAKDM4EPOLB
Orientin SCHEMBL13059270 0.82 L3MBTL1 (1.00) L3MBTL1CYP1A2GAAKDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006083666-A1 ANTI-INFLAMMATORY SUPPLEMENT COMPOSITIONS AND REGIMENS TO REDUCE CARDIOVASCULAR DISEASE RISKS A.M. TODD COMPANY (US) 2006-08-10 WO disclosed