Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 7/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.39 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6072999 | 0.90 | PPARG (0.47) | PPARGCYP3A4RXRALPAR1LPAR5 | |
| SCHEMBL6073139 | 0.88 | PPARG (0.53) | PPARGCYP3A4RXRAPPARAMEN1 | |
| SCHEMBL6073149 | 0.88 | PPARG (0.48) | PPARGCYP3A4RXRAPPARALPAR1 | |
| SCHEMBL6073215 | 0.87 | PPARG (0.47) | PPARGCYP3A4RXRAPPARALPAR1 | |
| SCHEMBL6073141 | 0.83 | PPARA (0.56) | PPARGCYP3A4RXRAPPARAMEN1 | |
| SCHEMBL6072992 | 0.82 | PPARA (0.51) | PPARGCYP3A4RXRAPPARA | |
| SCHEMBL6073130 | 0.81 | PPARA (0.47) | PPARGCYP3A4RXRAPPARAMEN1 | |
| SCHEMBL5430617 | 0.81 | PPARG (0.57) | PPARGCYP3A4RXRAPPARAMEN1 | |
| SCHEMBL6073204 | 0.81 | PPARA (0.52) | PPARGCYP3A4RXRAPPARALPAR1 | |
| SCHEMBL6073155 | 0.79 | PPARG (0.50) | PPARGCYP3A4RXRAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006117743-A1 | SUBSTITUTED AROMATIC COMPOUNDS AS ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | claimed |
| WO-2006117743-A1 | SUBSTITUTED AROMATIC COMPOUNDS AS ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |