Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.47 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.46 |
| ▸ | SLC2A8 | Q9NY64 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.41 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6073139 | 0.92 | PPARG (0.53) | PPARGCYP3A4RXRASLC2A1NPC1 | |
| SCHEMBL6073195 | 0.89 | PPARG (0.44) | PPARGSLC2A4SLC2A8CYP3A4RXRA | |
| SCHEMBL6072992 | 0.89 | PPARA (0.51) | PPARGSLC2A4SLC2A8CYP3A4RXRA | |
| SCHEMBL6073089 | 0.87 | PPARG (0.51) | PPARGCYP3A4RXRALPAR1LPAR5 | |
| SCHEMBL6073149 | 0.84 | PPARG (0.48) | PPARGCYP3A4RXRALPAR1LPAR5 | |
| SCHEMBL6073155 | 0.82 | PPARG (0.50) | PPARGCYP3A4RXRASLC2A1NPC1 | |
| SCHEMBL6073141 | 0.82 | PPARA (0.56) | PPARGCYP3A4RXRANPC1PPARA | |
| SCHEMBL5423717 | 0.82 | PPARA (0.58) | PPARGCYP3A4RXRASLC2A1PPARA | |
| SCHEMBL6073345 | 0.81 | PPARA (0.57) | PPARGCYP3A4RXRAPPARA | |
| SCHEMBL6073206 | 0.81 | PPARA (0.54) | PPARGSLC2A4SLC2A8SLC2A1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006117743-A1 | SUBSTITUTED AROMATIC COMPOUNDS AS ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | claimed |
| WO-2006117743-A1 | SUBSTITUTED AROMATIC COMPOUNDS AS ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |