SCHEMBL6073450

SCHEMBL6073450

COc1ccc(S(=O)(=O)N(CC(=O)O)Cc2ccc(OCCc3nc(-c4ccccc4)oc3C)cc2)cc1

nearest known ligand 0.72

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 19/20 0.72
PPARG P37231 18/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5227428 0.87 PPARG (0.75) PPARAPPARG
SCHEMBL5229077 0.86 PPARG (0.73) PPARAPPARG
SCHEMBL13720807 0.85 PPARG (0.70) PPARAPPARG
SCHEMBL5228991 0.84 PPARG (0.70) PPARAPPARG
SCHEMBL5451604 0.84 PPARG (0.96) PPARAPPARG
SCHEMBL6073703 0.83 PPARA (0.84) PPARAPPARG
Muraglitazar SCHEMBL676469 0.83 PPARA (1.00) PPARAPPARG
SCHEMBL14361124 0.82 PPARA (0.61) PPARAPPARG
SCHEMBL13718704 0.82 PPARG (1.00) PPARAPPARG
SCHEMBL5225239 0.81 PPARA (0.62) PPARAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006117743-A1 SUBSTITUTED AROMATIC COMPOUNDS AS ANTIDIABETIC AGENTS RANBAXY LABORATORIES LIMITED (IN) 2006-11-09 WO disclosed