Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | PPARA | Q07869 | 5/20 | 0.39 |
| ▸ | PPARG | P37231 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | DRD5 | P21918 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6073183 | 0.94 | NPSR1 (0.52) | NPSR1PPARAPPARGLMNAALDH1A1 | |
| SCHEMBL6073002 | 0.94 | NPSR1 (0.51) | NPSR1PPARAPPARGLMNAALDH1A1 | |
| SCHEMBL6073297 | 0.93 | NPSR1 (0.47) | NPSR1LMNAALDH1A1DRD2DRD1 | |
| SCHEMBL6073165 | 0.92 | NPSR1 (0.49) | NPSR1PPARAPPARGLMNAALDH1A1 | |
| SCHEMBL6073462 | 0.91 | NPSR1 (0.45) | NPSR1LMNAALDH1A1DRD2DRD1 | |
| SCHEMBL6073121 | 0.91 | NPSR1 (0.48) | NPSR1PPARAPPARGLMNAALDH1A1 | |
| SCHEMBL6073174 | 0.89 | NPSR1 (0.49) | NPSR1LMNAALDH1A1TSHRMAPT | |
| SCHEMBL6073238 | 0.86 | NPSR1 (0.45) | NPSR1PPARAPPARGLMNAALDH1A1 | |
| SCHEMBL6073175 | 0.84 | PPARA (0.44) | NPSR1PPARAPPARGLMNAALDH1A1 | |
| SCHEMBL6073207 | 0.82 | PPARG (0.39) | PPARAPPARGDRD2DRD1DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006117743-A1 | SUBSTITUTED AROMATIC COMPOUNDS AS ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |