Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | DRD5 | P21918 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6073121 | 0.93 | NPSR1 (0.48) | NPSR1LMNAMAPTTSHRALDH1A1 | |
| SCHEMBL6073520 | 0.91 | NPSR1 (0.49) | NPSR1DRD2DRD1DRD5HRH1 | |
| SCHEMBL6073290 | 0.91 | DRD2 (0.39) | NPSR1DRD2DRD1DRD5HRH1 | |
| SCHEMBL6073297 | 0.90 | NPSR1 (0.47) | NPSR1DRD2DRD1DRD5HRH1 | |
| SCHEMBL6073174 | 0.88 | NPSR1 (0.49) | NPSR1LMNAMAPTTSHRALDH1A1 | |
| SCHEMBL6073183 | 0.87 | NPSR1 (0.52) | NPSR1LMNAMAPTTSHRALDH1A1 | |
| SCHEMBL6073002 | 0.87 | NPSR1 (0.51) | NPSR1LMNAMAPTTSHRALDH1A1 | |
| SCHEMBL6073165 | 0.85 | NPSR1 (0.49) | NPSR1LMNAMAPTTSHRALDH1A1 | |
| SCHEMBL6073063 | 0.83 | TSHR (0.41) | NPSR1LMNATSHRALDH1A1 | |
| SCHEMBL6073238 | 0.82 | NPSR1 (0.45) | NPSR1DRD2DRD1DRD5HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006117743-A1 | SUBSTITUTED AROMATIC COMPOUNDS AS ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |