Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KCNN4 | O15554 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.33 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.33 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.33 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27565399 | 0.79 | KCNN4 (0.53) | TSHRKIF11MAPK1KCNN4ALDH1A1 | |
| SCHEMBL297786 | 0.75 | MAPK1 (0.52) | TSHRKIF11MAPK1KCNN4ALDH1A1 | |
| SCHEMBL8973 | 0.75 | KIF11 (0.48) | TSHRKIF11MAPK1KCNN4ALDH1A1 | |
| Fluoride SCHEMBL27919232 | 0.73 | KIF11 (0.46) | TSHRKIF11MAPK1KCNN4ALDH1A1 | |
| SCHEMBL28297324 | 0.73 | KIF11 (0.46) | TSHRKIF11MAPK1KCNN4ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL23726528 | 0.73 | KIF11 (0.46) | TSHRKIF11MAPK1KCNN4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28556207 | 0.73 | KIF11 (0.46) | TSHRKIF11MAPK1KCNN4ALDH1A1 | |
| Bromide SCHEMBL28557682 | 0.73 | KIF11 (0.46) | TSHRKIF11MAPK1KCNN4ALDH1A1 | |
| SCHEMBL16323365 | 0.72 | TSHR (0.50) | TSHRKIF11MAPK1KCNN4ALDH1A1 | |
| SCHEMBL11558547 | 0.71 | MAPK1 (0.48) | TSHRKIF11MAPK1KCNN4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1447408-A1 | Amino acid loaded trityl alcohol resins, method of production of amino acid loaded trityl alcohol resins and therapeutics produced therewith | Rohm and Haas Company (US) | 2004-08-18 | — | — | EP | claimed |
| US-20040158037-A1 | Amino acid loaded trityl alcohol resins, method of production of amino acid loaded trityl alcohol resins and biologically active substances and therapeutics produced therewith | BOHLING JAMES CHARLES (US) | 2004-08-12 | — | — | US | claimed |
| CN-114008058-B | Prodrugs of CDK inhibitors for the treatment of cancer | 润佳（苏州）医药科技有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-113993899-B | anti-CD 47 antibodies and uses thereof | 乐普生物科技股份有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-114008058-A | Prodrugs of CDK inhibitors for the treatment of cancer | 润佳（苏州）医药科技有限公司 | 2022-02-01 | — | — | CN | disclosed |
| CN-113993899-A | anti-CD 47 antibodies and uses thereof | 乐普生物科技股份有限公司 | 2022-01-28 | — | — | CN | disclosed |
| US-7049394-B2 | Method for preparing free flow resin | ROHM AND HAAS COMPANY (US) | 2006-05-23 | — | — | US | disclosed |
| EP-0781128-B1 | CLOTRIMAZOLE METABOLITES IN THE TREATMENT OF SICKLE CELL DISEASE | CHILDRENS MEDICAL CENTER (US) | 2005-11-23 | — | — | EP | disclosed |
| US-20050256298-A1 | Method for preparing free flow resin | MAIKNER JOHN J | 2005-11-17 | — | — | US | disclosed |
| US-20040209999-A1 | Method of manufacturing polypeptides, including T-20 and T-1249, at commercial scale, and polypeptide compositions related thereto | BOHLING JAMES CHARLES (US) | 2004-10-21 | — | — | US | disclosed |
| EP-1452538-A1 | Method of manufacturing T-20 and T-1249 peptides at commercial scale, and T-20 and T-1249 compositions related thereto | ROHM AND HAAS COMPANY (US) | 2004-09-01 | — | — | EP | disclosed |
| EP-1447408-A1 | Amino acid loaded trityl alcohol resins, method of production of amino acid loaded trityl alcohol resins and therapeutics produced therewith | Rohm and Haas Company (US) | 2004-08-18 | — | — | EP | disclosed |
| US-20040158037-A1 | Amino acid loaded trityl alcohol resins, method of production of amino acid loaded trityl alcohol resins and biologically active substances and therapeutics produced therewith | BOHLING JAMES CHARLES (US) | 2004-08-12 | — | — | US | disclosed |
| US-20040106774-A1 | Method for preparing free flow resin | ROHM AND HAAS COMPANY | 2004-06-03 | — | — | US | disclosed |
| EP-1391477-A1 | Method for preparing free flow resin | ROHM AND HAAS COMPANY (US) | 2004-02-25 | — | — | EP | disclosed |
| EP-0781128-A2 | CLOTRIMAZOLE METABOLITES IN THE TREATMENT OF SICKLE CELL DISEASE | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 1997-07-02 | — | — | EP | disclosed |
| WO-1996008242-A9 | CLOTRIMAZOLE METABOLITES IN THE TREATMENT OF SICKLE CELL DISEASE | — | 1996-06-27 | — | — | WO | disclosed |
| WO-1996008242-A2 | CLOTRIMAZOLE METABOLITES IN THE TREATMENT OF SICKLE CELL DISEASE | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 1996-03-21 | — | — | WO | disclosed |