SCHEMBL607463

SCHEMBL607463

NC(=O)NCCC[C@H](N)C(N)=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 2/20 0.44
OTC P00480 1/20 0.43
DDAH1 O94760 3/20 0.41
GNAI3 P08754 1/20 0.39
GNAO1 P09471 1/20 0.39
GNAI1 P63096 1/20 0.39
ARG1 P05089 1/20 0.38
RRM1 P23921 1/20 0.37
C3AR1 Q16581 1/20 0.35
ANPEP P15144 2/20 0.35
RNPEP Q9H4A4 2/20 0.35
DNPEP Q9ULA0 1/20 0.35
GSR P00390 1/20 0.34
CYP1A2 P05177 1/20 0.34
GLA P06280 1/20 0.34
TSHR P16473 1/20 0.34
NFKB1 P19838 1/20 0.34
APEX1 P27695 1/20 0.34
CYP2C19 P33261 1/20 0.34
NOS2 P35228 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3169670 1.00 DPP7 (0.44) DPP7OTCDDAH1GNAI3GNAO1
SCHEMBL18866881 1.00 DPP7 (0.44) DPP7OTCDDAH1GNAI3GNAO1
Succinic Acid SCHEMBL28261408 0.91 OTC (0.41) DPP7OTCDDAH1ARG1C3AR1
L-Citrulline SCHEMBL20587 0.85 OTC (0.59) OTCDDAH1ARG1GSRCYP1A2
SCHEMBL20951925 0.85 OTC (0.46) DPP7OTCDDAH1GNAI3GNAO1
L-Citrulline SCHEMBL15909604 0.85 OTC (0.59) OTCDDAH1ARG1GSRCYP1A2
L-Citrulline SCHEMBL9070200 0.85 OTC (0.59) OTCDDAH1ARG1GSRCYP1A2
L-Citrulline SCHEMBL22426116 0.85 OTC (0.59) OTCDDAH1ARG1GSRCYP1A2
L-Citrulline SCHEMBL4542892 0.85 OTC (0.59) OTCDDAH1ARG1GSRCYP1A2
L-Citrulline SCHEMBL437142 0.85 OTC (0.59) OTCDDAH1ARG1GSRCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118950437-A Photoelectric material based on ultrathin protein nano film, and preparation method and application thereof 陕西师范大学 2024-11-15 CN claimed
CN-118844429-A Protein-based agricultural chemical with reduced and enhanced efficacy 陕西师范大学 2024-10-29 CN claimed
EP-4153242-B1 PARA-AMINO-BENZYL LINKERS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN CONJUGATES SERVIER LAB (FR) 2024-05-15 EP claimed
EP-4153242-A1 PARA-AMINO-BENZYL LINKERS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN CONJUGATES Les Laboratoires Servier (FR) 2023-03-29 EP claimed
US-12370263-B2 Cyclic dinucleotide derivative based antibody-drug conjugates DAIICHI SANKYO COMPANY, LIMITED (JP) 2025-07-29 US disclosed
US-20250213685-A1 ANTI-EGFR ANTIBODY DRUG CONJUGATES ABBVIE INC (US) 2025-07-03 US disclosed
EP-4524154-A2 ANTIBODY-DRUG CONJUGATES OF CYCLIC DINUCLEOTIDE DERIVATIVES Daiichi Sankyo Company, Limited (JP) 2025-03-19 EP disclosed
US-12246196-B2 Antibody-drug conjugates comprising substituted benzo[e]pyrrolo[1,2-a][1,4]diazepines DAIICHI SANKYO COMPANY, LIMITED (JP) 2025-03-11 US disclosed
EP-3848054-B1 ANTIBODY-DRUG CONJUGATES OF CYCLIC DINUCLEOTIDE DERIVATIVES DAIICHI SANKYO CO LTD (JP) 2025-01-29 EP disclosed
CN-118950437-A Photoelectric material based on ultrathin protein nano film, and preparation method and application thereof 陕西师范大学 2024-11-15 CN disclosed
CN-118844429-A Protein-based agricultural chemical with reduced and enhanced efficacy 陕西师范大学 2024-10-29 CN disclosed
US-20240293567-A1 NOVEL CYCLIC DINUCLEOTIDE DERIVATIVE AND ANTIBODY-DRUG CONJUGATE THEREOF DAIICHI SANKYO COMPANY, LIMITED (JP) 2024-09-05 US disclosed
EP-1660507-B9 PROTEASOME INHIBITORS AND METHODS OF USING THE SAME CEPHALON INC (US) 2010-03-24 EP disclosed
US-20090291918-A1 PROTEASOME INHIBITORS AND METHODS OF USING THE SAME CEPHALON, INC. (US) 2009-11-26 US disclosed
US-7576206-B2 Proteasome inhibitors and methods of using the same CEPHALON, INC. (US) 2009-08-18 US disclosed
EP-1660507-B1 PROTEASOME INHIBITORS AND METHODS OF USING THE SAME CEPHALON INC (US) 2009-08-05 EP disclosed
EP-1660507-A2 PROTEASOME INHIBITORS AND METHODS OF USING THE SAME CEPHALON, INC. (US) 2006-05-31 EP disclosed
US-20050107307-A1 Proteasome inhibitors and methods of using the same TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2005-05-19 US disclosed
WO-2005021558-A2 PROTEASOME INHIBITORS AND METHODS OF USING THE SAME CEPHALON, INC. (US) 2005-03-10 WO disclosed
US-4997822-A Antitumor agents, treating AIDS ASTA PHARMA AKTIENGESELLSCHAFT (DE) 1991-03-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090291918-A1 PROTEASOME INHIBITORS AND METHODS OF USING THE SAME PSMB11, PSMB5, PSMB6 DPP7 1446/4885OTC 3716/4885DDAH1 992/4885
US-12370263-B2 Cyclic dinucleotide derivative based antibody-drug conjugates STING1, CGAS, CDA DPP7 1936/4885OTC 4532/4885DDAH1 474/4885
US-20250213685-A1 ANTI-EGFR ANTIBODY DRUG CONJUGATES EGFR, ERBB2, ERBB3 DPP7 1558/4885OTC 4746/4885DDAH1 2628/4885
US-20050107307-A1 Proteasome inhibitors and methods of using the same PSMB11, PSMB5, PSMB6 DPP7 1446/4885OTC 3716/4885DDAH1 992/4885
US-12246196-B2 Antibody-drug conjugates comprising substituted benzo[e]pyrrolo[1,2-a][1,4]diazepines CNTN1, BTN3A1, FABP6 DPP7 49/4885OTC 2879/4885DDAH1 339/4885
US-20240293567-A1 NOVEL CYCLIC DINUCLEOTIDE DERIVATIVE AND ANTIBODY-DRUG CONJUGATE THEREOF STING1, CGAS, TLR9 DPP7 1785/4885OTC 4383/4885DDAH1 545/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.